Evidence map›Paper›PMID 39213029›Full record

ArticleeLife2024

Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics.

Youxi Liu, Meimei Yin, Xiaoting Mao, Shuai Wu, Shuangping Wei, Shujun Heng, Yichun Yang, Jinwen Huang, Zhuolin Guo, Chuan Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. A single-cell spatial transcriptomic census of human skin anatomy.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Youxi Liu *State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0002-9084-1588
Meimei Yin *State Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0003-3718-1944
Xiaoting Mao *Zhejiang Yangshengtang Institute of Natural Medication Co Ltd, Hangzhou, China.
Shuai Wu *State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0002-7569-3986
Shuangping WeiZhejiang Yangshengtang Institute of Natural Medication Co Ltd, Hangzhou, China.
Shujun HengState Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.
Yichun YangState Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.
Jinwen HuangDepartment of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Zhuolin GuoDepartment of Dermatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Chuan LiZhejiang Yangshengtang Institute of Natural Medication Co Ltd, Hangzhou, China.
Chao JiDepartment of Dermatology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Liu HuZhejiang Yangshengtang Institute of Natural Medication Co Ltd, Hangzhou, China.
Wenjie LiuState Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0002-8044-5338
Ling-Juan ZhangState Key Laboratory of Cellular Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China.ORCID https://orcid.org/0000-0001-6937-4578

Funding

National Key Research and Development Program of China 2020YFA0112901National Key Research and Development Program of China 2023YFC2508100National Natural Science Foundation of China 81971551National Natural Science Foundation of China 82373879Xiamen University Double First Class Construction Project (Biology) DFC2024004
6 · The paper itself

Abstract

Allergic contact dermatitis (ACD), a prevalent inflammatory skin disease, is elicited upon repeated skin contact with protein-reactive chemicals through a complex and poorly characterized cellular network between immune cells and skin resident cells. Here, single-cell transcriptomic analysis of the murine hapten-elicited model of ACD reveals that upon elicitation of ACD, infiltrated CD4

Indexed as

Dermatitis, Allergic ContactDisease Models, AnimalAnimalsCD8-Positive T-LymphocytesCytokinesFemaleFibroblastsGene Expression ProfilingInterferon-gammaInterferon gamma ReceptorMiceMice, Inbred C57BLReceptors, CXCR3Receptors, InterferonSingle-Cell AnalysisSkinCytokinesInterferon-gammaInterferon gamma ReceptorReceptors, CXCR3Receptors, InterferonAllergic contact dermatitisdermal fibroblastsIFNγimmunologyinflammationmousepreadipocytesSkin inflammationtype 1 inflammation

Identifiers

PMID39213029
PMCPMC11364439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.