Evidence map›Paper›PMID 39212884›Full record

ArticleDoklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections2024

Age Specifics of Homeostasis Response to Cold Stress in Wistar Rats: Endurance Improvement or Disorganization?

M V Kondashevskaya, K A Artemyeva, V V Aleksankina, E B Manukhina, L M Mikhaleva

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M V KondashevskayaAvtsyn Institute of Human Morphology, Petrovsky National Research Center of Surgery, Moscow, Russia. marivladiko@mail.ru.
K A ArtemyevaAvtsyn Institute of Human Morphology, Petrovsky National Research Center of Surgery, Moscow, Russia.
V V AleksankinaAvtsyn Institute of Human Morphology, Petrovsky National Research Center of Surgery, Moscow, Russia.
E B ManukhinaInstitute of General Pathology and Pathophysiology, Moscow, Russia.
L M MikhalevaAvtsyn Institute of Human Morphology, Petrovsky National Research Center of Surgery, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold exposure, especially in combination with exercise, is a common procedure to fortify the body. However, its effects in old age are poorly understood. Using the homeostasis stability coefficient as an indicator, the body response to a 20-min swim in cold water was for the first time studied comprehensively in old and young Wistar rats. Effects on the hormonal, hematological, and morphofunctional systems of the liver and thymus were assessed. Unfavorable age-related changes in the stability of homeostasis were observed in old rats. The changes complicated the recovery after cold stress and required the involvement of a greater number of homeostatic mechanisms than in young rats. The liver was found to be the most vulnerable to cold stress. It was concluded that fortifying the body by cold exposure is possible to use in old age, but with due regard to age-related restrictions.

Indexed as

Cold TemperatureHomeostasisLiverRats, WistarAgingAnimalsCold-Shock ResponseMaleRatsStress, PhysiologicalThymus Glandadaptationbiological indicatorscold stressendurance improvementhomeostasis stability coefficientyoung and old rats

Identifiers

PMID39212884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.