Evidence map›Paper›PMID 39212840›Full record

ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2024

Gastrointestinal Health Benefits of Sorghum Phenolics.

Ibtesam Sleem, Dmitriy Smolensky, Vermont Dia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Germination Paradox in Sorghum: A Review.Foods (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ibtesam SleemDepartment of Food Science, University of Tennessee, 2510 River Drive, Knoxville, TN, 37996, USA.
Dmitriy SmolenskyU.S. Department of Agriculture, Grain Quality and Structure Research Unit, Agricultural Research Service, 1515 College Ave, Manhattan, KS, 66502, USA.
Vermont DiaDepartment of Food Science, University of Tennessee, 2510 River Drive, Knoxville, TN, 37996, USA. vdia@utk.edu.

Funding

USDA-ARS NACA 58-3020-0-023
6 · The paper itself

Abstract

Sorghum is considered a promising food security crop and remarkable rich source of bioactive components including phenolic acids, flavonoids, and tannins. Sorghum phenolics exhibited numerous protective effects against multiple chronic diseases. However, there is no review of the effects of sorghum phenolics on gastrointestinal (GI) health. Specifically, recent studies have highly suggested that sorghum phenolics can maintain gastrointestinal homeostasis and enhance microbial diversity and richness. Furthermore, sorghum phenolics showed GI anticancer effects in both in vitro and in vivo studies against colorectal and esophageal cancers. Treatment of GI related human cancer cell lines stimulated apoptosis and suppressed proliferation. Sorghum intake and extracts treatments reduced intestinal oxidative stress and inflammatory mediators in human and in vivo studies. In addition, understanding the role and mechanisms underlying gastrointestinal health benefits of sorghum phenolics is crucial to determine treatment strategies of different GI diseases.

Indexed as

Gastrointestinal TractPhenolsSorghumAnimalsApoptosisFlavonoidsGastrointestinal DiseasesGastrointestinal MicrobiomeHumansOxidative StressPlant ExtractsFlavonoidsPhenolsPlant ExtractsChemopreventionGastrointestinal healthMicrobiomePhenolicsSorghum

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.