ArticleGeroScience2025
Association between self-reported difficulty in chewing or swallowing and frailty in older adults: A retrospective cohort study.
Article in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Interferential current stimulation during dental facial treatment improves masticatory function.Scientific reports · 2026Trial
- Oral functional limitation and risk of frailty onset in older adults: a sex-stratified 4-Year cohort study with competing risk analysis.GeroScience · 2026Article
- A Machine Learning-Derived Risk Scorecard for Pneumonia Hospitalization in Japanese Old-Old Adults.Geriatrics & gerontology international · 2026Article
- The Longitudinal Associations of Denture Use and Subjective Chewing Difficulty with Depressive Symptoms Among Middle-Aged and Older Adults: A Sex-Stratified Analysis of the Korean Longitudinal Study of Aging (2006-2022).Healthcare (Basel, Switzerland) · 2026Article
- Cultural Adaptation and Validation of the Oral Frailty Index-8 for Turkish Older Adults.Gerodontology · 2026Article
- Oral Frailty as a Marker of Intrinsic Capacity Decline: A Narrative Review on a Multisystemic Ageing Perspective.Journal of oral rehabilitation · 2026Review
- Oral Frailty and Multidimensional Health Among Community-Dwelling Older Adults in China: A Cross-Sectional Study.Nutrients · 2026Article
- oral functional limitation and long-term frailty trajectories: a 6-year cohort study of community-dwelling older adults in Korea.GeroScience · 2026Article
- Masticatory function and frailty: insights from NHANES and CHARLS.BMC public health · 2026Article
- Article
- The Effect of Tooth Loss on Depression and Anxiety Among Older Adults in China: The Mediating Role of Dietary Diversity.Nutrients · 2026Article
- Prevalence and associated factors of oral frailty in elderly patients undergoing elective surgery: a secondary analysis of a cross-sectional study.Frontiers in medicine · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Oral frailty can contribute to physical and mental health disorders. Previous research has shown an association between frailty and self-reported difficulty in chewing or swallowing. However, their combined assessment has obscured their specific impact on frailty-related outcomes. To investigate the independent associations between difficulty in chewing or swallowing and 1-year frailty outcomes, while also examining their interactions. This retrospective cohort study utilized the DeSC database to identify older adults aged ≥ 75 years who underwent health checkups between April 2014 and November 2022. Multivariate Cox regression analyses were conducted to assess the association between self-reported difficulty in chewing or swallowing and outcomes, including hospitalization due to aspiration pneumonia, all-cause hospitalization, and all-cause mortality within 1 year. Interactions between chewing and swallowing difficulties were also evaluated. Among 359,111 older adults, 39.0% reported oral function difficulties. Swallowing difficulty alone lacked significant outcome association. However, chewing difficulty alone was significantly associated with higher risks of hospitalization due to aspiration pneumonia (hazard ratio (HR), 1.35; 95% confidence interval (CI), 1.15-1.58; P < 0.001), all-cause hospitalization (HR, 1.08; 95% CI, 1.05-1.11; P < 0.001), and all-cause mortality (HR, 1.28; 95% CI, 1.14-1.44; P < 0.001) compared with no self-reported difficulty. A significant positive interaction between self-reported difficulty in chewing and swallowing was observed for all-cause mortality (P = 0.009). Self-reported difficulty in chewing was significantly associated with higher risks of hospitalization due to aspiration pneumonia, all-cause hospitalization, and all-cause mortality among older adults. Chewing and swallowing difficulties showed a synergistic effect, significantly increasing all-cause mortality risk.
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