Evidence map›Paper›PMID 39212770›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

One day of environment-induced heat stress damages the murine myocardium.

Melissa Roths, Tori E Rudolph, Swathy Krishna, Alyona Michael, Joshua T Selsby

Abstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Acute anomalous high-temperature exposure impacts on mouse ovaries.Journal of assisted reproduction and genetics · 2026
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melissa RothsDepartment of Animal Science, Iowa State University, Ames, Iowa, United States.ORCID 0000-0001-8814-9130
Tori E RudolphDepartment of Animal Science, Iowa State University, Ames, Iowa, United States.ORCID 0009-0003-0071-3684
Swathy KrishnaDepartment of Animal Science, Iowa State University, Ames, Iowa, United States.ORCID 0000-0002-6595-0862
Alyona MichaelVeterinary Diagnostic Laboratory, Iowa State University College of Veterinary Medicine, Ames, Iowa, United States.ORCID 0000-0002-5616-6953
Joshua T SelsbyDepartment of Animal Science, Iowa State University, Ames, Iowa, United States.ORCID 0000-0003-3797-7539

Funding

U.S. Department of Agriculture (USDA) 2020-02716
6 · The paper itself

Abstract

The physiological consequences of environment-induced heat stress (EIHS), caused by prolonged exposure to excess heat and humidity, are largely unknown. The purpose of this investigation was to determine the extent to which EIHS alters cardiac health. We hypothesized that 24 h of EIHS would cause cardiac injury and cellular dysfunction in a murine EIHS model. To test this hypothesis, 7-wk-old female mice were housed under thermoneutral (TN) conditions (

Indexed as

Heat Stress DisordersMyocardiumAnimalsAutophagyBody TemperatureDisease Models, AnimalEndoplasmic Reticulum StressFemaleHeat-Shock ProteinsHeat-Shock ResponseHSP27 Heat-Shock ProteinsMiceMice, Inbred C57BLMitochondria, HeartMyocytes, CardiacTime FactorsHeat-Shock ProteinsHSP27 Heat-Shock ProteinsHspb2 protein, mouseclimate changeheat strokemusclethermic injury

Identifiers

PMID39212770
PMCPMC11482254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.