Evidence map›Paper›PMID 39212735›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Cantharidin and sodium fluoride attenuate the negative inotropic effect of the A

R Schwarz, B Hofmann, U Gergs, J Neumann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Inotropic effects of retatrutide in isolated human atrial preparations.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  2. Review
  3. Contractile effects of retatrutide in isolated mouse atrial preparations.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
  4. Article
  5. Inhibition of protein phosphatases attenuates ANaunyn-Schmiedeberg's archives of pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

R SchwarzMedical Faculty, Institute for Pharmacology and Toxicology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
B HofmannCardiac Surgery, Medizinische Fakultät, Martin-Luther-Universität Halle-Wittenberg, 06097, Halle, Germany.
U GergsMedical Faculty, Institute for Pharmacology and Toxicology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
J NeumannMedical Faculty, Institute for Pharmacology and Toxicology, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany. Joachim.neumann@medizin.uni-halle.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cantharidin and sodium fluoride inhibit the activity of serine/threonine protein phosphatases 1 (PP1) and 2A (PP2A) and increase the force of contraction in human atrial preparations. R-phenylisopropyl adenosine (R-PIA) acts as an agonist at A

Indexed as

AdenosineAdenosine A1 Receptor AgonistsCantharidinHeart AtriaMyocardial ContractionReceptor, Adenosine A1Sodium FluorideAgedAnimalsFemaleHumansMiceMiddle AgedAdenosineAdenosine A1 Receptor AgonistsCantharidinReceptor, Adenosine A1Sodium FluorideAdenosine receptorCantharidinHuman atriumMouse atriumPhosphatasesSodium fluoride

Identifiers

PMID39212735
PMCPMC11825636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.