Evidence map›Paper›PMID 39212168›Full record

ArticleACR open rheumatology2024

Expanded CD8

Jose Rubio, Morgane Humbel, Lama Mulki, Eri Katsuyama, Suzanne Krishfield, Julianne O'Connell, George C Tsokos, Vasileios Kyttaris

Abstract read
In one paragraph

Article in ACR open rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jose RubioBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Morgane HumbelBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.ORCID https://orcid.org/0000-0001-6145-5947
Lama MulkiBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Eri KatsuyamaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Suzanne KrishfieldBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Julianne O'ConnellBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
George C TsokosBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.ORCID https://orcid.org/0000-0001-9589-2360
Vasileios KyttarisBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.ORCID https://orcid.org/0000-0001-7652-3826

Funding

Harvard Clinical and Translational Science CenterUM1TR004408 · NCATS · HARVARD MEDICAL SCHOOL · PI Lindsey Robert Baden, Lee Marshall Nadler · 2023 to 2026
$43.3M
T cells in LupusR01AI148161 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TSOKOS, GEORGE C · 2020 to 2024
$2.2M
Harvard Catalyst UM1TR004408National Institute of Allergy and Infectious Diseases 5RO1AI148161NCATS NIH HHS UM1 TR004408NIAID NIH HHS R01 AI148161
6 · The paper itself

Abstract

objectiveOne of the leading causes of morbidity and mortality among patients with systemic lupus erythematosus (SLE) is infections. The expression of the ectonucleotidase CD38 on the surface of CD8

methodsA cohort of 80 patients with SLE were recruited over 18 months. The rate of clinically significant infections and presence of CD8

resultsA total of 20 infections were registered over the study period. We observed that the patients with an expanded CD8

conclusionHigh levels of CD8

Identifiers

PMID39212168
PMCPMC11638141

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.