Evidence map›Paper›PMID 39212043›Full record

ReviewStroke2024

Not So Transient?: A Narrative Review on Cognitive Impairment After Transient Ischemic Attack.

Alexander Hayes, Scott E Kasner, Christopher G Favilla, Aaron Rothstein, Jens Witsch, Roy H Hamilton, Kelly L Sloane

Abstract readReview
In one paragraph

Review in Stroke, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander HayesDepartment of Medicine, University of Oxford, United Kingdom (A.H.).ORCID 0000-0001-6245-1016
Scott E KasnerDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0003-0418-6917
Christopher G FavillaDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0003-0871-9549
Aaron RothsteinDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0002-8480-8220
Jens WitschDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0001-8924-851X
Roy H HamiltonDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0002-9958-1946
Kelly L SloaneDepartment of Neurology (S.E.K., C.G.F., A.R., J.W., R.H.H., K.L.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID 0000-0001-9680-9565

Funding

Neutrophil extracellular traps and high-precision MRI measures of tissue injury after intracerebral hemorrhageK23NS131588 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI WITSCH, JENS JULIAN · 2024 to 2024
$231k
American Heart Association-American Stroke Association 23CDA1053561NINDS NIH HHS K23 NS131588
6 · The paper itself

Abstract

Transient ischemic attack (TIA) is traditionally viewed as a self-resolving episode of neurological change without persistent impairments and without evidence of acute brain injury on neuroimaging. However, emerging evidence suggests that TIA may be associated with lingering cognitive dysfunction. Cognitive impairment is a prevalent and disabling sequela of ischemic stroke, but the clinical relevance of this phenomenon after TIA is less commonly recognized. We performed a literature search of observational studies of cognitive function after TIA. There is a consistent body of literature suggesting that rates of cognitive impairment following TIA are higher than healthy controls, but the studies included here are limited by heterogeneity in design and analysis methods. We go on to summarize recent literature on proposed pathophysiological mechanisms underlying the development of cognitive impairment following TIA and finally suggest future directions for further research in this field.

Indexed as

Cognitive DysfunctionIschemic Attack, TransientHumansbrain injuriesclinical relevancecognitive dysfunctionischemic attack, transientneuroimaging

Identifiers

PMID39212043
PMCPMC11421974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.