Evidence map›Paper›PMID 39211618›Full record

ReviewJACS Au2024

Decarboxylation in Natural Products Biosynthesis.

Nguyet A Nguyen, Jacob H Forstater, John A McIntosh

Abstract readReview
In one paragraph

Review in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Biomimetic Synthesis of Seven Halenaquinone Meroterpenoids.Journal of the American Chemical Society · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Discovery of the Phosphonate Flavophos Produced byJournal of the American Chemical Society · 2026
    Article
  9. Article
  10. Article
  11. Halogenated Vitamin BACS omega · 2026
    Article
  12. Discovery of the Phosphonate Flavophos Produced bybioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nguyet A NguyenMerck & Co., Inc., Boston, Massachusetts, 02115, United States.
Jacob H ForstaterMerck & Co., Inc., Rahway, New Jersey, 07065, United States.ORCID https://orcid.org/0000-0003-0268-1009
John A McIntoshMerck & Co., Inc., Boston, Massachusetts, 02115, United States.ORCID https://orcid.org/0000-0002-9487-490X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decarboxylation reactions are frequently found in the biosynthesis of primary and secondary metabolites. Decarboxylase enzymes responsible for these transformations operate via diverse mechanisms and act on a large variety of substrates, making them appealing in terms of biotechnological applications. This Perspective focuses on the occurrence of decarboxylation reactions in natural product biosynthesis and provides a perspective on their applications in biocatalysis for fine chemicals and pharmaceuticals.

Identifiers

PMID39211618
PMCPMC11350588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.