Evidence map›Paper›PMID 39211515›Full record

ArticleEuropean heart journal. Case reports2024

Percutaneous patent foramen ovale closure for hypoxaemia at the age of 73: a case report showing immediate benefit.

Lars S Witte, Bart Straver, Berto J Bouma, Robbert J de Winter, Marcel A M Beijk

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Linking patent foramen ovale with atrial cardiomyopathy: a narrative review of clinical signals, electrophysiology, and translational opportunities.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lars S WitteCAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Amsterdam, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-0159-0754
Bart StraverCAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Amsterdam, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Berto J BoumaCAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Amsterdam, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-1433-9692
Robbert J de WinterCAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Amsterdam, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
Marcel A M BeijkCAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Amsterdam, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-7984-3021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Approximately 25% of the general population has a patent foramen ovale (PFO) that remains asymptomatic in the vast majority. Right-to-left shunt (RLS)-mediated hypoxaemia is a rare associated condition of PFO. Case summary: This report describes a case of percutaneous PFO closure for hypoxaemia in a 73-year-old patient showing immediate clinical benefit. She experienced progressive dyspnoea on exertion requiring oxygen therapy. SaO2 was 87% at rest without oxygen therapy, which increased to 98% after percutaneous PFO closure. Discussion: Most PFOs remain clinically insignificant but RLS-mediated hypoxaemia is a rare phenomenon that can occur even at advanced age. Percutaneous PFO closure is a safe and effective therapy option that provides immediate improvement of hypoxaemia.

Indexed as

Case reportHypoxaemiaPatent foramen ovalePercutaneous closureRight-to-left shunt

Identifiers

PMID39211515
PMCPMC11358635

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.