ReviewFrontiers in endocrinology2024
Research progress of ultrasound in accurate evaluation of cartilage injury in osteoarthritis.
Review in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Comparison of Ultrasonographic, Radiographic, Computed Tomographic, and Ex Vivo Measurements of Feline Femoral Trochlear Groove Depth.Animals : an open access journal from MDPI · 2026Article
- Multidimensional Quality Evaluation of Imaging Performance for Musculoskeletal Ultrasound Computed Tomography System.Bioengineering (Basel, Switzerland) · 2026Article
- High-frequency ultrasound semi-quantitative assessment of cartilage damage in rheumatoid arthritis using the outcome measures in rheumatology scoring system.Quantitative imaging in medicine and surgery · 2026Article
- Realistic Ultrasound Simulations of Healthy and Osteoarthritic Cartilage.Journal of imaging · 2026Article
- Musculoskeletal Ultrasound and Protein-Based Hydrogels: Novel Approaches for the Diagnosis and Treatment of Sports Injuries.Polymers · 2026Review
- Assessment of morphology, radiopacity gradient and mechanical properties of articular cartilage with contrast-enhanced high-resolution peripheral quantitative computed tomography.Frontiers in bioengineering and biotechnology · 2026Article
- Xuetongsu attenuates bone destruction in rheumatoid arthritis by suppressing RANKL/RANK/NFATc1 pathway to inhibit osteoclastogenesis and bone resorption.Bone & joint research · 2025Article
- Comparison of knee articular cartilage thickness across sex and age groups in healthy adults.Journal of experimental orthopaedics · 2025Article
- Nanoparticle-enabled molecular imaging diagnosis of osteoarthritis.Materials today. Bio · 2025Review
- Ultrasonography as an Early Evaluation Tool for Posttraumatic Osteoarthritis in Wistar Rats (Rattus norvegicus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Therapeutic prospects and potential mechanisms of Prdx6: as a novel target in musculoskeletal disorders.Frontiers in physiology · 2025Review
- Innovations in collagen-network remodeling and extracellular matrix mechanics: toward a new era in articular cartilage repair.Frontiers in bioengineering and biotechnology · 2025Review
- Developing the new diagnostic model by integrating bioinformatics and machine learning for osteoarthritis.Journal of orthopaedic surgery and research · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is a prevalent cause of joint algesia, loss of function, and disability in adults, with cartilage injury being its core pathological manifestation. Since cartilage damage is non-renewable, the treatment outcome in the middle and late stages of OA is unsatisfactory, which can be minimized by changing lifestyle and other treatment modalities if diagnosed and managed in the early stages, indicating the importance of early diagnosis and monitoring of cartilage injury. Ultrasound technology has been used for timely diagnosis and even cartilage injury treatment, which is convenient and safe for the patient owing to no radiation exposure. Studies have demonstrated the effectiveness of ultrasound and its various quantitative ultrasound parameters, like ultrasound roughness index (URI), reflection coefficient (R), apparent integrated backscatter (AIB), thickness, and ultrasound elastography, in the early and accurate assessment of OA cartilage pathological changes, including surface and internal tissue, hardness, and thickness. Although many challenges are faced in the clinical application of this technology in diagnosis, ultrasound and ultrasound-assisted techniques offer a lot of promise for detecting early cartilage damage in OA. In this review, we have discussed the evaluation of ultrasonic cartilage quantitative parameters for early pathological cartilage changes.
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