ArticleACS sustainable chemistry & engineering2024
Sustainable One-Pot Production and Scale-Up of the New Platform Chemical Diformylxylose (DFX) from Agricultural Biomass.
Article in ACS sustainable chemistry & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Simultaneous Lignin Fractionation and Functionalization under Mild Conditions via Reactive Extraction.ACS omega · 2026Article
- From Pigment Chemistry to Nanomaterials: Fungal Pigments as Reducing and Stabilizing Agents in Green Nanoparticle Synthesis.Microorganisms · 2026Review
- Biomass-Derived Diformylxylose as a Renewable Solvent for Biocatalysis Applications.ChemSusChem · 2026Article
- Sustainable thermal paper formulation using lignocellulosic biomass fractions.Science advances · 2026Article
- Xylose Acetals - a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation.ChemSusChem · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The large-scale production of platform chemicals from biomass requires efficient, cost-effective, and sustainable methods. Here, we present three one-pot synthesis routes for producing diformylxylose (DFX), a sugar-based solvent and platform chemical, using d-xylose or corncobs as feedstocks. With yields of approximately 80%, these routes were seamlessly scaled from lab to kilogram-scale in a 15 L batch reactor. Techno-economic assessment demonstrates the competitiveness of the proposed methods against fossil- and biobased analogues. Life-cycle analysis shows the potential of these processes to reduce environmental and societal impacts from cradle to gate. At the "end of life", DFX is demonstrated to be inherently biodegradable. Overall, we present a compelling case study of scaling a novel platform chemical guided by techno-economic and environmental concerns leading to balanced cost-competitiveness and life-cycle sustainability.
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Registered trials
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