Evidence map›Paper›PMID 39211333›Full record

ArticleNAR genomics and bioinformatics2024

Progerin mRNA expression in non-HGPS patients is correlated with widespread shifts in transcript isoforms.

Reynold Yu, Huijing Xue, Wanru Lin, Francis S Collins, Stephen M Mount, Kan Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NAR genomics and bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Reynold YuDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, MD, USA.
Huijing XueDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, MD, USA.
Wanru LinDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, MD, USA.
Francis S CollinsMolecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0002-1023-7410
Stephen M MountDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, MD, USA.ORCID https://orcid.org/0000-0003-2748-8205
Kan CaoDepartment of Cell Biology and Molecular Genetics, University of Maryland College Park, MD, USA.ORCID https://orcid.org/0000-0002-5806-2939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature aging disease caused primarily by a C1824T mutation in

Identifiers

PMID39211333
PMCPMC11358823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.