Evidence map›Paper›PMID 39211297›Full record

ArticleFrontiers in natural products2022

Gambogic acid: Multi-gram scale isolation, stereochemical erosion toward epi-gambogic acid and biological profile.

Gary E Arevalo, Michelle K Frank, Katelin S Decker, Maria A Theodoraki, Emmanuel A Theodorakis

Abstract read
In one paragraph

Article in Frontiers in natural products, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gary E ArevaloDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States.
Michelle K FrankDepartment of Biology, Arcadia University, Glenside, PA, United States.
Katelin S DeckerDepartment of Biology, Arcadia University, Glenside, PA, United States.
Maria A TheodorakiDepartment of Biology, Arcadia University, Glenside, PA, United States.ORCID 0000-0002-0775-8928
Emmanuel A TheodorakisDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, United States.ORCID 0000-0001-9845-6919

Funding

Chemical design of amyloid targeting fluorescent probesRF1AG062362 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI THEODORAKIS, EMMANUEL A, YANG, JERRY · 2018 to 2020
$2.1M
Development of selective amyloid-responsive fluorescent probesRF1AG077802 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YANG, JERRY · 2022 to 2022
$1.9M
NIA NIH HHS RF1 AG062362NIA NIH HHS RF1 AG077802
6 · The paper itself

Abstract

Introduction: Extracted from gamboge resin, gambogic acid ( Methods: We report here an efficient method that allows multigram scale isolation of Results and Discussion: We found that

Indexed as

breast cancergambogegarcinianatural productsynthetic methods

Identifiers

PMID39211297
PMCPMC11361287

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.