Evidence map›Paper›PMID 39210952›Full record

ArticleBio-protocol2024

Tetrazine Amino Acid Encoding for Rapid and Complete Protein Bioconjugation.

Alex J Eddins, Abigail H Pung, Richard B Cooley, Ryan A Mehl

Abstract read
In one paragraph

Article in Bio-protocol, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alex J EddinsDepartment of Biochemistry and Biophysics, Oregon State University, 2011 Agricultural and Life Sciences, Corvallis, OR, USA.
Abigail H PungDepartment of Biochemistry and Biophysics, Oregon State University, 2011 Agricultural and Life Sciences, Corvallis, OR, USA.
Richard B CooleyDepartment of Biochemistry and Biophysics, Oregon State University, 2011 Agricultural and Life Sciences, Corvallis, OR, USA.
Ryan A MehlDepartment of Biochemistry and Biophysics, Oregon State University, 2011 Agricultural and Life Sciences, Corvallis, OR, USA.

Funding

The GCE4All Center: Unleashing the Potential of Genetic Code Expansion for Biomedical ResearchRM1GM144227 · NIGMS · OREGON STATE UNIVERSITY · PI RYAN A MEHL · 2022 to 2026
$6.2M
NIGMS NIH HHS RM1 GM144227
6 · The paper itself

Abstract

Generating protein conjugates using the bioorthogonal ligation between tetrazines and

Indexed as

1245-tetrazine (Tet)Aminoacyl tRNA synthetase/tRNA pair (aaRS/tRNA)BioorthogonalGenetic code expansion (GCE)Near-cognate suppressionNoncanonical amino acid (ncAA)Strained trans-cyclooctene (sTCO)

Identifiers

PMID39210952
PMCPMC11349492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.