Evidence map›Paper›PMID 39210439›Full record

ArticleJournal of orthopaedic surgery and research2024

The study findings demonstrated a significant association between C-reactive protein levels and trabecular bone score : NHANES 2005-2008.

Huangze Yan, Shenjie Wang, Huikun Cao, Haobo Zhong, Chunhan Sun

Abstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Huangze YanGuangdong Medical University, Zhanjiang, 524000, Guangdong, China.
Shenjie WangDepartment of Orthopedics, Huizhou Central People's Hospital, Huizhou, China.
Huikun CaoGuangdong Medical University, Zhanjiang, 524000, Guangdong, China.
Haobo ZhongGuangdong Medical University, Zhanjiang, 524000, Guangdong, China. 402161066@qq.com.
Chunhan SunGuangdong Medical University, Zhanjiang, 524000, Guangdong, China. sunchunhan@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe association between C-reactive protein and bone density has been primarily investigated in previous studies, with little to no research investigating its relationship with total bone trabecular score.

methodsData from the NHANES database (500 males and 633 females) were utilized in this study to perform a multiple weighted linear regression analysis to estimate this relationship of CRP and TBS. Subsequently, population characterization, univariate logistic regression analysis, subgroup and interaction analysis were in progress.

resultsUpon covariate adjustment, the analysis revealed a notable negative correlation between CRP and TBS(β=-0.0081,95% CI (-0.0142, -0.0019), P = 0.009). Furthermore, no interactions were detected within any subgroups.

conclusionThis finding enhances our comprehension of the relationship in inflammation and bone health, offering the novel research outlook for the treatment and prevention of osteoporosis and osteoporotic fractures.

Indexed as

Bone DensityCancellous BoneC-Reactive ProteinNutrition SurveysAdultAgedFemaleHumansMaleMiddle AgedOsteoporosisC-Reactive ProteinC-reactive proteinInflammationTotal TBS

Identifiers

PMID39210439
PMCPMC11360293

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