Evidence map›Paper›PMID 39210321›Full record

ArticleBMC cancer2024

Prognostic significance and treatment strategies for IKZF1 deletion in pediatric B-cell precursor acute lymphoblastic leukemia.

Lili Pan, Yiqiao Chen, Kaizhi Weng, Biyun Guo, Shuquan Zhuang, Shuxian Huang, Zhulan Lian, Xiaofang Wang, Nainong Li, Yongzhi Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. [Research progress on copy number alterations in pediatric B-cell acute lymphoblastic leukemia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lili Pan *Fujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China.
Yiqiao Chen *Fujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China.
Kaizhi WengDepartment of Pediatric Hematology, Rheumatology and Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
Biyun GuoDepartment of Pediatrics, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Shuquan ZhuangDepartment of Pediatrics, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.
Shuxian HuangDepartment of Pediatric Hematology, Rheumatology and Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
Zhulan LianDepartment of Pediatrics, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Xiaofang WangDepartment of Pediatrics, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China.
Nainong LiFujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China. nainli@aliyun.com.
Yongzhi ZhengFujian Provincial Key Laboratory on Hematology, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fuzhou, China. brandy850728@163.com.

Funding

Fujian Provincial Clinical Research Center for Hematological Malignancies 2020Y2006Joint Funds for the Innovation of Science and Technology, Fujian Province 2020Y9052National Key Clinical Specialty Discipline Construction Program of China 2021-76Startup Fund for Scientific Research, Fujian Medical University 2021QH1049
6 · The paper itself

Abstract

backgroundThe predictive importance of IKZF1

methodsIKZF1 status was reliably determined in 804 patients using multiplex ligation-dependent probe amplification (MLPA) data obtained from four hospitals in Fujian, a province of China. In the Chinese Children Leukemia Group (CCLG)-ALL 2008 cohort, IKZF1 status was included in the risk assignment, with all IKZF1

resultsIKZF1

conclusionsThe prognostic effect of IKZF1

Indexed as

Ikaros Transcription FactorNeoplasm, ResidualPrecursor B-Cell Lymphoblastic Leukemia-LymphomaAdolescentChildChild, PreschoolChinaFemaleGene DeletionHumansInfantMalePrognosisIkaros Transcription FactorIKZF1 protein, humanIKZF1 deletionMinimal residual disease-guided protocolPediatric B-cell precursor acute lymphoblastic leukemia

Identifiers

PMID39210321
PMCPMC11363382

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.