Evidence map›Paper›PMID 39210312›Full record

ArticleBMC public health2024

Associations of ambient air pollution and lifestyle with the risk of NAFLD: a population-based cohort study.

Xinxin Kong, Ruyu Huang, Rui Geng, Jingwei Wu, Jiong Li, Yaqian Wu, Yang Zhao, Dongfang You, Hao Yu, Mulong Du and 4 more

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xinxin Kong *Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Ruyu Huang *Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Rui GengDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Jingwei WuDepartment of Epidemiology and Biostatistics, College of Public Health, Temple University, Philadelphia, PA, 19122, USA.
Jiong LiDepartment of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Yaqian WuDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Yang ZhaoDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Dongfang YouDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Hao YuDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Mulong DuDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China.
Zihang ZhongDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. zhzhong@njmu.edu.cn.
Ling LiDepartment of Endocrinology, Zhong Da Hospital Southeast University, Nanjing, 210009, China. lingli@seu.edu.cn.
Senmiao NiDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. senmiaoni@njmu.edu.cn.
Jianling BaiDepartment of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 211166, China. baijianling@njmu.edu.cn.ORCID 0000-0002-9845-5198

Funding

National Natural Science Foundation of China 82273738
6 · The paper itself

Abstract

backgroundBoth ambient air pollution and lifestyle factors contribute to the incidence of non-alcoholic fatty liver disease (NAFLD), but previous studies usually focused on single-factor associations. We aimed to assess the joint associations of ambient air pollution and lifestyle with the NAFLD risk and investigate whether lifestyle modifies the association of air pollution with NAFLD risk.

methodsA total of 417,025 participants from the UK Biobank were included in this study. Annual average concentrations of NO

results4752 (1.14%) incident NAFLD events were recorded. Long-term exposure to air pollutants and an unhealthy lifestyle were significantly associated with the increased risk of incident NAFLD. Lifestyle was the primary factor of incident NAFLD, with a PAF of 37.18% (95% CI: 29.67%, 44.69%). In addition, a significant additive interaction between air pollution and lifestyle for NAFLD risk was observed (RERI: 0.36, 95% CI: 0.09-0.63).

conclusionsLong-term exposure to ambient air pollutants and poor lifestyle were jointly associated with a higher risk of NAFLD.

Indexed as

Air PollutionLife StyleNon-alcoholic Fatty Liver DiseaseAdultAgedAir PollutantsCohort StudiesEnvironmental ExposureFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsRisk FactorsUnited KingdomAir PollutantsAir PollutionAssociationLifestyleNon-alcoholic fatty liver diseaseUK Biobank

Identifiers

PMID39210312
PMCPMC11363520

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.