Evidence map›Paper›PMID 39210309›Full record

ArticleBMC pulmonary medicine2024

Prediction models for postoperative pulmonary complications in intensive care unit patients after noncardiac thoracic surgery.

Xiangjun He, Meiling Dong, Huaiyu Xiong, Yukun Zhu, Feng Ping, Bo Wang, Yan Kang

Abstract read
In one paragraph

Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiangjun HeDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China.
Meiling DongDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China.
Huaiyu XiongDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China.
Yukun ZhuDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China.
Feng PingDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China.
Bo WangDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China. wchicu@126.com.
Yan KangDepartment of Critical Care Medicine, West China Hospital, Sichuan University and Institute of Critical Care Medicine, No. 17, Section 3, Renmin South Road, Wuhou District, Chengdu City, Sichuan Province, 610041, China. kangyan@scu.edu.cn.

Funding

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University ZYGD23012National Key Research and Development Program of China 2022YFC2504500
6 · The paper itself

Abstract

backgroundPostoperative pulmonary complication (PPC) is a leading cause of mortality and poor outcomes in postoperative patients. No studies have enrolled intensive care unit (ICU) patients after noncardiac thoracic surgery, and effective prediction models for PPC have not been developed. This study aimed to explore the incidence and risk factors and construct prediction models for PPC in these patients.

methodsThis study retrospectively recruited patients admitted to the ICU after noncardiac thoracic surgery at West China Hospital, Sichuan University, from July 2019 to December 2022. The patients were randomly divided into a development cohort and a validation cohort at a 70% versus 30% ratio. The preoperative, intraoperative and postoperative variables during the ICU stay were compared. Univariate and multivariate logistic regression analyses were applied to identify candidate predictors, establish prediction models, and compare the accuracy of the models with that of reported risk models.

resultsA total of 475 ICU patients were enrolled after noncardiac thoracic surgery (median age, 58; 72% male). At least one PPC occurred in 171 patients (36.0%), and the most common PPC was pneumonia (153/475, 32.21%). PPC significantly increased the duration of mechanical ventilation (p < 0.001), length of ICU stay (p < 0.001), length of hospital stay (LOS) (p < 0.001), and rate of reintubation (p = 0.047) in ICU patients. Seven risk factors were identified, and then the prediction nomograms for PPC were constructed. At ICU admission, the area under the curve (AUC) was 0.766, with a sensitivity of 0.71 and specificity of 0.60; after extubation, the AUC was 0.841, with a sensitivity of 0.75 and specificity of 0.83. The models showed robust discrimination in both the development cohort and the validation cohort, and they were well calibrated and more accurate than reported risk models.

conclusionsICU patients who underwent noncardiac thoracic surgery were at high risk of developing PPCs. Prediction nomograms were constructed and they were more accurate than reported risk models, with excellent sensitivity and specificity. Moreover, these findings could help assess individual PPC risk and enhance postoperative management of patients.

Indexed as

Intensive Care UnitsPostoperative ComplicationsAdultAgedChinaFemaleHumansIncidenceLength of StayLung DiseasesMaleMiddle AgedRespiration, ArtificialRetrospective StudiesRisk AssessmentRisk FactorsIntensive care unitNomogramNoncardiac thoracic surgeryPostoperative pulmonary complicationsRisk factor

Identifiers

PMID39210309
PMCPMC11360767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.