ArticleEJNMMI physics2024
Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner.
Article in EJNMMI physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- First ex-vivo positronium imaging of tissues with modular J-PET scanner usingZeitschrift fur medizinische Physik · 2026Article
- First positronium lifetime imaging usingScientific reports · 2026Article
- GATE 10 Monte Carlo particle transport simulation: I. Development and new features.Physics in medicine and biology · 2026Article
- Improved random coincidence estimation including triple coincidence detection in PET.Frontiers in nuclear medicine · 2026Article
- High-Resolution Positronium Lifetime Tomography at Clinical Activity Levels on the PennPET Explorer.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Phantom imaging demonstration of positronium lifetime with a long axial field-of-view PET/CT andEJNMMI physics · 2025Article
- First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT.Frontiers in nuclear medicine · 2025Article
- High-resolution positronium lifetime tomography by the method of moments.Physics in medicine and biology · 2024Article
- Comparative analysis of positron emitters for theranostic applications based on small bioconjugates highlightingEJNMMI physics · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundPositron emission tomography (PET) traditionally uses coincident annihilation photons emitted from a positron interacting with an electron to localize cancer within the body. The formation of positronium (Ps), a bonded electron-positron pair, has not been utilized in clinical applications of PET due to the need to detect either the emission of a prompt gamma ray or the decay of higher-order coincident events. Assessment of the lifetime of the formed Ps, however, can potentially yield additional diagnostic information of the surrounding tissue because Ps properties vary due to void size and molecular composition. To assess the feasibility of measuring Ps lifetimes with a PET scanner, experiments were performed in a Biograph Vision Quadra (Siemens Healthineers). Quadra is a long-axial field-of-view (LA-FOV) PET scanner capable of producing list-mode data from single interaction events.
resultsOrtho-Ps (o-Ps) lifetimes were measured for quartz-glass and polycarbonate samples using a
conclusionOverall, the methodology presented in this manuscript demonstrates the repeatability of Ps lifetime measurements with clinically available isotopes in a commercially-available LA-FOV PET scanner. This validation work lays the foundation for future in-vivo patient scans with Quadra.
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