ArticleStroke and vascular neurology2025
Predictors of malignant swelling in space-occupying cerebellar infarction.
Article in Stroke and vascular neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Age-Related Volumetric Changes of the Posterior Cranial Fossa and its Structures in Stroke Patients.Cerebellum (London, England) · 2026Article
- Diagnostic Pitfalls of CT in Malignant Superior Cerebellar Artery Infarction: Implications for Treatment Decisions and Future Management Strategies.Journal of clinical medicine · 2025Article
- Comparison of the ABC/2 formula with computer-assisted volumetry of ischemic cerebellar stroke.PloS one · 2025Article
- Functional Outcomes After Decompressive Surgery in Patients with Malignant Space-Occupying Cerebellar Infarction.Neurology international · 2024Article
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12 authors.
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Abstract
backgroundMalignant swelling is a fatal complication that can occur abruptly in space-occupying cerebellar infarction. We aimed to establish markers that predict malignant swelling in cerebellar infarction.
methodsWe retrospectively analysed data of stroke patients who were treated in our hospital between 2014 and 2020. Malignant swelling was defined as a mass effect in the posterior cranial fossa, accompanied by a decrease in consciousness due to compression of the brainstem and/or the development of obstructive hydrocephalus. Statistical analyses were performed on multiple variables to identify predictors of malignant swelling.
resultsAmong 7284 stroke patients, we identified 487 patients with an infarct in the cerebellum. 93 patients were suitable for analysis having space-occupying cerebellar infarction. 33 of 93 (35.5%) patients developed malignant swelling. Multivariable analysis revealed infarct volume as the main predictor being independently associated with the development of malignant swelling with a cut-off infarct volume of 38 cm
conclusionsInfarct volume was the key significant predictor of malignant swelling in space-occupying cerebellar infarction. With many cases of malignant swelling occurring after more than 72 hours, we advocate prolonged neurological monitoring.
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