Evidence map›Paper›PMID 39209512›Full record

ArticleHIV medicine2024

Cardiovascular disease risk in people of African ancestry with HIV in the United Kingdom.

Stephanie Ko, Lourdes Dominguez-Dominguez, Zoe Ottaway, Lucy Campbell, Julie Fox, Fiona Burns, Lisa Hamzah, Andrew Ustianowski, Amanda Clarke, Stephen Kegg and 5 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HIV medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05685810 (Genetic and Clinical Determinants of Cardiovascular Disease, Diabetes, Kidney Disease and Obesity in People of African Ancestry With HIV), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05685810 active not recruitingnot on this map

Genetic and Clinical Determinants of Cardiovascular Disease, Diabetes, Kidney Disease and Obesity in People of African Ancestry With HIV

Typeobservational_patient_registrySponsorKing's College Hospital NHS TrustRan2018 to 2030Enrolled3,029ConditionsHIV Nephropathy, Kidney Injury, Kidney Diseases, Diabetes Mellitus
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stephanie KoKing's College Hospital NHS Foundation Trust, London, UK.
Lourdes Dominguez-DominguezKing's College Hospital NHS Foundation Trust, London, UK.ORCID 0000-0001-6018-9026
Zoe OttawayKing's College Hospital NHS Foundation Trust, London, UK.ORCID 0009-0008-9425-7662
Lucy CampbellKing's College Hospital NHS Foundation Trust, London, UK.
Julie FoxKing's College London, London, UK.
Fiona BurnsRoyal Free London NHS Foundation Trust, London, UK.
Lisa HamzahSt Georges University Hospital NHS Foundation Trust, London, UK.
Andrew UstianowskiManchester University NHS Foundation Trust, Manchester, UK.
Amanda ClarkeUniversity Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Stephen KeggLewisham and Greenwich NHS Trust, London, UK.
Sarah SchoemanLeeds Teaching Hospitals NHS Trust, Leeds, UK.
Rachael JonesChelsea and Westminster NHS Foundation Trust, London, UK.
Sarah L PettInstitute for Global Health, University College London, London, UK.
Jonathan HudsonKing's College Hospital NHS Foundation Trust, London, UK.ORCID 0000-0002-5128-8388
Frank A PostKing's College Hospital NHS Foundation Trust, London, UK.ORCID 0000-0002-2844-1612

Funding

Gilead Sciences IN-UK-983-6053Guy's and St Thomas' Charity EIC180702Medical Research Council (UK) Confidence in Concept scheme MC_PC_17164
6 · The paper itself

Abstract

objectivesOur objective was to describe the prevalence of cardiovascular disease (CVD) risk factors in people of African ancestry with HIV in the UK.

methodsWe conducted a cross-sectional analysis of CVD risk factors in Black people with HIV aged ≥40 years and estimated the 10-year CVD risk using QRISK®3-2018. Correlations between body mass index (BMI) and CVD risk factors were described using Pearson correlation coefficients, and factors associated with 10-year CVD risk ≥5% were described using logistic regression.

resultsWe included 833 Black people with HIV and a median age of 54 years; 54% were female, 50% were living with obesity (BMI ≥30 kg/m

conclusionsWe report a high burden of CVD risk factors, including obesity, hypertension, and diabetes mellitus, in people of African ancestry with HIV in the UK. BMI-focused interventions in these populations may improve CVD risk while also addressing other important health issues.

Indexed as

Black PeopleBody Mass IndexCardiovascular DiseasesHeart Disease Risk FactorsHIV InfectionsAdultAgedCross-Sectional StudiesDiabetes MellitusFemaleHumansHypertensionMaleMiddle AgedObesityPrevalenceBlackBMICVD riskGLP‐1 agonistsHIVobesitystatins

Identifiers

PMID39209512
PMCPMC11608579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.