Evidence map›Paper›PMID 39209433›Full record

ReviewInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2024

Assessing minimally invasive simple hysterectomy in low risk cervical cancer: set up for the LASH trial.

Nicolò Bizzarri, Nadeem R Abu-Rustum, Marie Plante, Pedro T Ramirez, Luis Chiva, Henrik Falconer, David Cibula, Denis Querleu, Francesco Fanfani, Anna Fagotti and 1 more

Abstract readReview
In one paragraph

Review in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Minimally invasive simple hysterectomy in low-risk cervical cancer: a single-arm trial with stopping rules (ENGOT-cx23/MITO/LASH trial).International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2025
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicolò BizzarriUOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy nicolo.bizzarri@yahoo.com.ORCID 0000-0002-1727-904X
Nadeem R Abu-RustumDepartment of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-9689-1298
Marie PlanteDepartment of Obstetrics and Gynecology, Centre Hospitalier Universitaire de Quebec, Quebec, Quebec, Canada.
Pedro T RamirezDepartment of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, Texas, USA.ORCID 0000-0002-6370-8052
Luis ChivaClinica Universidad de Navarra Departamento de Ginecologia y Obstetricia, Pamplona, Spain.ORCID 0000-0002-1908-3251
Henrik FalconerDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
David CibulaDepartment of Obstetrics and Gynecology, University of Prague, Prague, Czech Republic.
Denis QuerleuUOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0002-3984-4812
Francesco FanfaniUOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-1991-7284
Anna FagottiUOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Giovanni ScambiaUOC Ginecologia Oncologica, Dipartimento di Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.ORCID 0000-0003-2758-1063

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Network Lead Academic Participating Site: Memorial Sloan Kettering Cancer CenterUG1CA233290 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CAROL AGHAJANIAN, Darren Feldman · 2019 to 2026
$10.2M
NCI NIH HHS P30 CA008748NCI NIH HHS UG1 CA233290
6 · The paper itself

Abstract

After the publication of the Laparoscopic Approach to Cervical Cancer (LACC) trial, open surgery has become the standard approach for radical hysterectomy in early stage cervical cancer. Recent studies assessed the role of a non-radical approach in low risk cervical cancer and showed no survival difference compared with radical hysterectomy. However, there is a gap in knowledge regarding the oncologic outcomes of minimally invasive simple hysterectomy in low risk cervical cancer. This review offers an overview of the current evidence on the role of the minimally invasive approach in low risk cervical cancer and raises the need for a new clinical trial in this setting.

Indexed as

HysterectomyMinimally Invasive Surgical ProceduresUterine Cervical NeoplasmsFemaleHumansLaparoscopyCervix UteriHysterectomyLaparoscopesLaparotomyRobotic Surgical Procedures

Identifiers

PMID39209433
PMCPMC12068377

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.