Evidence map›Paper›PMID 39208993›Full record

ArticleTheoretical population biology2024

Joint identity among loci under mutation and regular inbreeding.

Marcy K Uyenoyama

Abstract read
In one paragraph

Article in Theoretical population biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Marcy K UyenoyamaDepartment of Biology, Duke University, Box 90338, Durham, NC 27708-0338, USA. Electronic address: marcy@duke.edu.

Funding

MATHEMATICAL POPULATION GENETICSR01GM037841 · NIGMS · DUKE UNIVERSITY · PI UYENOYAMA, MARCY K · 1986 to 2013
$1.5M
NIGMS NIH HHS R01 GM037841
6 · The paper itself

Abstract

This study describes a compact method for determining joint probabilities of identity-by-state (IBS) within and between loci in populations evolving under genetic drift, crossing-over, mutation, and regular inbreeding (partial self-fertilization). Analogues of classical indices of associations among loci arise as functions of these joint identities. This coalescence-based analysis indicates that multi-locus associations reflect simultaneous coalescence events across loci. Measures of association depend on genetic diversity rather than allelic frequencies, as do linkage disequilibrium and its relatives. Scaled indices designed to show monotonic dependence on rates of crossing-over, inbreeding, and mutation may prove useful for interpreting patterns of genome-scale variation.

Indexed as

InbreedingMutationGene FrequencyGenetic DriftGenetic LociGenetics, PopulationGenetic VariationHumansLinkage DisequilibriumModels, GeneticEffective numberLinkage disequilibriumMating systemSelfingTwo-locus identity

Identifiers

PMID39208993
PMCPMC11495244

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.