Evidence map›Paper›PMID 39208112›Full record

ArticleScience (New York, N.Y.)2024

A smart mask for exhaled breath condensate harvesting and analysis.

Wenzheng Heng, Shukun Yin, Jihong Min, Canran Wang, Hong Han, Ehsan Shirzaei Sani, Jiahong Li, Yu Song, Harry B Rossiter, Wei Gao

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

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  17. Low-Temperature Ammonia Sensing Using Sulfurized WSSensors (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenzheng HengAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0009-0009-5278-0727
Shukun YinAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-8218-9219
Jihong MinAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-5788-1473
Canran WangAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0003-3297-9041
Hong HanAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-2852-8662
Ehsan Shirzaei SaniAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-4609-1505
Jiahong LiAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-7938-9589
Yu SongAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-4185-2256
Harry B RossiterDivision of Respiratory and Critical Care Physiology and Medicine, Institute for Respiratory Medicine and Exercise Physiology, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0002-7884-0726
Wei GaoAndrew and Peggy Cherng Department of Medical Engineering, Division of Engineering and Applied Science, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-8503-4562

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Novel cardiopulmonary exercise testing variables to differentiate neuromuscular deconditioning from diseaseR01HL166850 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI Harry B Rossiter · 2023 to 2026
$3.1M
Laser-Engraved Wearable Sweat Sensors to Detect and Monitor Cardiometabolic DiseaseR01HL155815 · NHLBI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GAO, WEI · 2021 to 2025
$2.0M
Cutaneous uric acid and metabolite monitoring to improve individual response to pharmaceutical and dietary treatment in patients with goutR21DK132666 · NIDDK · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI FITZGERALD, JOHN D, GAO, WEI · 2022 to 2023
$461k
NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS R01 HL155815NHLBI NIH HHS R01 HL166850NIDDK NIH HHS R21 DK132666
6 · The paper itself

Abstract

Recent respiratory outbreaks have garnered substantial attention, yet most respiratory monitoring remains confined to physical signals. Exhaled breath condensate (EBC) harbors rich molecular information that could unveil diverse insights into an individual's health. Unfortunately, challenges related to sample collection and the lack of on-site analytical tools impede the widespread adoption of EBC analysis. Here, we introduce EBCare, a mask-based device for real-time in situ monitoring of EBC biomarkers. Using a tandem cooling strategy, automated microfluidics, highly selective electrochemical biosensors, and a wireless reading circuit, EBCare enables continuous multimodal monitoring of EBC analytes across real-life indoor and outdoor activities. We validated EBCare's usability in assessing metabolic conditions and respiratory airway inflammation in healthy participants, patients with chronic obstructive pulmonary disease or asthma, and patients after COVID-19 infection.

Indexed as

Breath TestsExhalationMasksAsthmaBiomarkersBiosensing TechniquesCOVID-19HumansPulmonary Disease, Chronic ObstructiveRespiratory Tract DiseasesSpecimen HandlingBiomarkers

Identifiers

PMID39208112
PMCPMC12168143

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.