Evidence map›Paper›PMID 39206852›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2024

Design, synthesis, and biological activity evaluation of dihydromyricetin derivatives against SARS-CoV-2-Omicron virus.

Cong Wu, Qi Jiang, Hui Zhong, Xudong Zhou, Leping Liu, Tong Pan, Chao Liu, Wei Wang, Wenbing Sheng

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cong WuSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Qi JiangSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Hui ZhongSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Xudong ZhouSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Leping LiuTCM and Ethnomedicine Innovation and Development International Laboratory, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Tong PanSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Chao LiuZhangjiajie Meicha Technology Research Center Hunan Qiankun Biotechnology Co., Ltd, Zhangjiajie, People's Republic of China.
Wei WangSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.
Wenbing ShengSchool of Pharmacy, Hunan University of Chinese Medicine, Changsha, Hunan, People's Republic of China.ORCID 0000-0002-9780-0033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An oxidising and substituting one-pot reaction strategy has been developed to synthesise dihydromyricetin derivatives with the aim of enhancing the inhibitory activity of dihydromyricetin against SARS-CoV-2. Different

Indexed as

Antiviral AgentsDrug DesignFlavonolsSARS-CoV-2AnimalsChlorocebus aethiopsCoronavirus 3C ProteasesDose-Response Relationship, DrugHumansMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipVero CellsVirus ReplicationAntiviral AgentsCoronavirus 3C ProteasesdihydromyricetinFlavonolsDihydromyricetinflavoneOmicron virus BA.5SARS-CoV-2 3CLprosynthesis

Identifiers

PMID39206852
PMCPMC11363738

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.