Evidence map›Paper›PMID 39206552›Full record

ArticleCirculation research2024

Systems Biology Approach Uncovers Candidates for Liver-Heart Interorgan Crosstalk in HFpEF.

Stefano Strocchi, Luo Liu, Rongling Wang, Steffen P Häseli, Federico Capone, David Bode, Natasha Nambiar, Tolga Eroglu, Leandro Santiago Padilla, Catherine Farrelly and 10 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  10. SALVE: prediction of interorgan communication with transcriptome latent space representation.American journal of physiology. Heart and circulatory physiology · 2025
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  17. The Cardiohepatic Axis in Metabolic Disease: Liver to Heart.JACC. Basic to translational science · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Stefano Strocchi *Deutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0009-0002-8879-6156
Luo Liu *Deutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
Rongling WangDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0000-0001-8719-938X
Steffen P HäseliDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0000-0002-8933-3236
Federico CaponeDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
David BodeDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0000-0003-4077-111X
Natasha NambiarGerman Centre for Cardiovascular Research (DZHK), Partner Site Berlin, Germany (S.S., L.L., R.W., S.P.H., F.C., D.B., N.N., T.E., L.S.P., M.M., C.U.O., U.K., G.G.S.).ORCID 0009-0004-3538-8081
Tolga ErogluDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
Leandro Santiago PadillaDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0000-0002-0873-7205
Catherine FarrellyTranslational Approaches in Heart Failure and Cardiometabolic Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (F.C., N.N., L.S.P., C.F., A.V., S.J., G.G.S.).
Antonio VaccaTranslational Approaches in Heart Failure and Cardiometabolic Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (F.C., N.N., L.S.P., C.F., A.V., S.J., G.G.S.).ORCID 0000-0003-0051-7723
Marianna MascagniDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
Christian U OeingDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
Ulrich KintscherInstitute of Pharmacology, Max Rubner Center for Cardiovascular Metabolic Renal Research (U.K.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0000-0001-7386-0990
Simone JungTranslational Approaches in Heart Failure and Cardiometabolic Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (F.C., N.N., L.S.P., C.F., A.V., S.J., G.G.S.).
Saskia A DiezelDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.
Sarah V Liévano ContrerasDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.ORCID 0009-0000-9967-0108
Mingqi ZhouDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, University of California, Irvine (M.Z., M.S.).ORCID 0009-0007-7643-7873
Marcus SeldinDepartment of Biological Chemistry, Center for Epigenetics and Metabolism, University of California, Irvine (M.Z., M.S.).ORCID 0000-0001-8026-4759
Gabriele G SchiattarellaDeutsches Herzzentrum der Charité (S.S., L.L., R.W., S.P.H., F.C., D.B., T.E., L.S.P., M.M., C.U.O., S.A.D., S.V.L.C., G.G.S.), Charité-Universitätsmedizin Berlin, Germany.

Funding

Integrative approaches to dissection of endocrine communicationDP1DK130640 · NIDDK · UNIVERSITY OF CALIFORNIA-IRVINE · PI SELDIN, MARCUS MICHAEL · 2021 to 2025
$3.2M
NIDDK NIH HHS DP1 DK130640
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart FailureLiverSystems BiologyAnimalsHumansMyocardiumStroke Volumeheart failurelivermetabolismnon-alcoholic fatty liver diseasesystems biology

Identifiers

PMID39206552
PMCPMC11427132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.