Evidence map›Paper›PMID 39206428›Full record

ArticleOTO open

Augmented Reality-Guided Frozen Section Analysis: Bringing the Pathologist From the Laboratory to the Operating Room.

Marina Aweeda, Liyu Huang, Alexander N Perez, Kim A Ely, Mitra Mehrad, James S Lewis, Michael C Topf

Abstract read
In one paragraph

Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marina AweedaDepartment of Otolaryngology-Head and Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA.ORCID 0000-0001-9360-9592
Liyu HuangDepartment of Otolaryngology-Head and Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA.
Alexander N PerezDepartment of Pathology Microbiology and Immunology, Vanderbilt University Medical Center Nashville Tennessee USA.
Kim A ElyDepartment of Pathology Microbiology and Immunology, Vanderbilt University Medical Center Nashville Tennessee USA.
Mitra MehradDepartment of Pathology Microbiology and Immunology, Vanderbilt University Medical Center Nashville Tennessee USA.
James S LewisDepartment of Laboratory Medicine and Pathology Mayo Clinic Phoenix Arizona USA.
Michael C TopfDepartment of Otolaryngology-Head and Neck Surgery Vanderbilt University Medical Center Nashville Tennessee USA.ORCID 0000-0002-1022-4417

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
Augmented Reality to Guide Head and Neck Cancer SurgeryK08CA293255 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Michael Topf · 2024 to 2026
$645k
NCI NIH HHS K08 CA293255NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

Due to the anatomic complexity of the head and neck and variable proximity between laboratory and operating room (OR), effective communication during frozen section analysis (FSA) between surgeons and pathologists is challenging. This proof-of-concept study investigates an augmented reality (AR) protocol that allows pathologists to virtually join the OR from the laboratory. Head and neck cancer specimens were scanned ex vivo using a 3-dimensional scanner and uploaded into an AR platform. Eight head and neck specimens were discussed by surgeons and pathologists in an AR environment. AR-guided intraoperative consultation was used for specimen orientation and discussion of FSA margin sampling sites. One patient had positive initial margins on FSA and was re-resected to negative final margins. AR-guided FSA is possible and allows pathologists to join the operating from any location for intraoperative discussion.

Indexed as

augmented realityfrozen section analysishead and neck cancerhead and neck surgeryintraoperative communication

Identifiers

PMID39206428
PMCPMC11351170

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.