Evidence map›Paper›PMID 39206413›Full record

ArticleMedComm2024

Patient-derived ovarian cancer organoid carries immune microenvironment and blood vessel keeping high response to cisplatin.

Yuqing Zhao, Chen Wang, Wei Deng, Lanyang Li, Jiping Liu, Yanghua Shi, Xiang Tao, Jian Zhang, Qi Cao, Chunhui Cai and 1 more

Abstract read
In one paragraph

Article in MedComm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Re-Thinking Pharmacokinetics in Ovarian Cancer: What Do Organoids Add?International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuqing ZhaoObstetrics & Gynecology Hospital Fudan University Shanghai China.
Chen WangDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Wei DengLongHua Hospital Shanghai University of Traditional Chinese Medicine Shanghai China.
Lanyang LiDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Jiping LiuDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Yanghua ShiDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Xiang TaoObstetrics & Gynecology Hospital Fudan University Shanghai China.
Jian ZhangDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Qi CaoObstetrics & Gynecology Hospital Fudan University Shanghai China.
Chunhui CaiDepartment of Research Shanghai LiSheng Biotech Shanghai China.
Xinxin HanDepartment of Research Shanghai LiSheng Biotech Shanghai China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is high recurrence and mortality malignant tumor. The most common ovarian cancer was High-Grade Serous Ovarian Cancer. However, High-Grade Serous Ovarian Cancer organoid is rare, which organoid with patient immune microenvironment and blood vessels even absence. Here, we report a novel High-Grade Serous Ovarian Cancer organoid system derived from patient ovarian cancer samples. These organoids recapitulate High-Grade Serous Ovarian Cancer organoids' histological and molecular heterogeneity while preserving the critical immune microenvironment and blood vessels, as evidenced by the presence of

Indexed as

cisplatinorganoidovarian cancertumor microenvironment (TME)vascularization

Identifiers

PMID39206413
PMCPMC11351687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.