ArticleFrontiers in medicine2024
Relationship between systemic immune-inflammation index and osteoarthritis: a cross-sectional study from the NHANES 2005-2018.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Modulation Effects of Reproductive Hormones on Oogenesis in a Collagenase-Induced Osteoarthritis Mouse Model.Biomedicines · 2026Article
- The association between life's crucial 9 and osteoarthritis in US adults: the mediating role of central adiposity.Nutrition & metabolism · 2026Article
- Systemic inflammation partially mediates the association between lipid accumulation and osteoarthritis in normal BMI adults.Scientific reports · 2025Article
- Associations of METS-VF and BRI with risk of osteoarthritis in patients with diabetes or prediabetes: evidence from the NHANES 1999-2020.Frontiers in endocrinology · 2025Article
- Association between dietary index for gut microbiota and osteoarthritis in the US population: the mediating role of systemic immune-inflammation index.Frontiers in nutrition · 2025Article
- Inflammatory indicators derived from complete blood counts in relation to osteoarthritis prevalence: findings from the NHANES 2007-2020 cross-sectional survey.Experimental biology and medicine (Maywood, N.J.) · 2025Article
- The association between social determinants, lifestyle and metabolic factors and the onset of secondary glenohumeral joint osteoarthritis: a cohort study of adults in the UK.Frontiers in public health · 2025Article
- Association between geriatric nutritional risk index and osteoarthritis in aged person over 60: data from NHANES 2005-2018.Frontiers in medicine · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
Objective: The study aimed to explore the relationship between systemic inflammatory response index (SIRI) levels and osteoarthritis (OA) using cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) database from 2005 to 2018. Methods: Using cross-sectional data from the NHANES database from 2005 to 2018, we included 11,381 study participants divided into OA ( Results: This study enrolled 11,381 participants aged ≥20 years, including 1,437 (14%) with OA. Weighted multivariable regression analysis in the fully adjusted Model 3 indicated a correlation between higher levels of SIRI (log Conclusion: The positive correlation between SIRI and OA risk, with a critical value of 4.757, holds clinical value in practical applications. Additionally, our study indicates that SIRI is a novel, clinically valuable, and convenient inflammatory biomarker that can be used to predict OA risk in adults.
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