Evidence map›Paper›PMID 39206160›Full record

ArticleFrontiers in oncology2024

Immune-related intestinal pseudo-obstruction caused by immune checkpoint inhibitors: case report.

Yimeng Qian, Zheng Zhi, Jing Ai, Lin Kang, Gang Qiu, Xin Huang, Jing Zhao

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Yimeng Qian *Department of Oncology, Hebei General Hospital, Shijiazhuang, China.
Zheng Zhi *Department of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Jing AiDepartment of Oncology, Hebei General Hospital, Shijiazhuang, China.
Lin KangDepartment of Pathology, Hebei General Hospital, Shijiazhuang, China.
Gang QiuDepartment of Oncology, Hebei General Hospital, Shijiazhuang, China.
Xin HuangDepartment of Oncology, Hebei General Hospital, Shijiazhuang, China.
Jing ZhaoDepartment of Oncology, Hebei General Hospital, Shijiazhuang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal obstruction, a rare manifestation of immunotherapy-related gastrointestinal adverse events, can be severe and even life-threatening with intestinal perforation. We present a 64-year-old man with HCC and currently under the therapy with Pembrolizumab, who was admitted in our hospital with abdominal distension. Radiologic findings were consistent with small bowel ileus. After conservative treatment, the patient underwent colonoscopy where no cause of ileus was discovered. The patient received high-dose prednisone due to the side effects of immune checkpoint inhibitor therapy. This resulted in a gradual improvement of symptoms.

Indexed as

adverse effectsbloatingconstipationimmune checkpoint inhibitorimmune-related pseudo-obstruction

Identifiers

PMID39206160
PMCPMC11349563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.