Evidence map›Paper›PMID 39205921›Full record

ArticleInternational journal of reproductive biomedicine2024

The regulatory roles of Smad2/3 protein and

Marzieh Ghorbani, Marzieh Sanoee Farimani, Iraj Khodadadi, Sina Mohagheghi, Iraj Amiri, Heidar Tayebinia

Abstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marzieh GhorbaniDepartment of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Marzieh Sanoee FarimaniDepartment of Obstetrics and Gynecology, Medicine School, Hamadan University of Medical Sciences, Hamadan, Iran.
Iraj KhodadadiDepartment of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Sina MohagheghiDepartment of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Iraj AmiriFertility and Infertility Research Centre, Hamadan University of Medical Sciences, Hamadan, Iran.
Heidar TayebiniaDepartment of Clinical Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The impaired functions of granulosa cells (GCs) in the delayed development and immaturity of oocytes have been reported in polycystic ovary syndrome (PCOs). Even with ovarian stimulation, a large number of oocytes in these patients are still in the stage germinal vesicle (GV). Objective: The levels of Smad2/3, phosphorylated Smad2/3 (P-Smad2/3), the expression of Materials and Methods: GCs of MII and GV oocytes were isolated from 38 women with PCOs and the expression levels of Results: The expression level of Conclusion: It seems that P-Smad2/3 plays a role in oocyte development, and the downregulation of this protein is associated with a defect in the maturation of GV oocytes. On the other hand, the upregulation of the

Indexed as

Granulosa cell.OocytesPolycystic ovary

Identifiers

PMID39205921
PMCPMC11347763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.