Evidence map›Paper›PMID 39205678›Full record

ArticlemicroLife2024

Resistance against aminoglycoside antibiotics via drug or target modification enables community-wide antiphage defense.

Larissa Kever, Qian Zhang, Aël Hardy, Philipp Westhoff, Yi Yu, Julia Frunzke

Abstract read
In one paragraph

Article in microLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Larissa KeverInstitute of Bio-und Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich 52425, Germany.
Qian ZhangDepartment of Gastroenterology, Zhongnan Hospital of Wuhan University, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, School of Pharmaceutical Sciences, Wuhan University, 185 East Lake Road, Wuhan 430071, China.
Aël HardyInstitute of Bio-und Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich 52425, Germany.
Philipp WesthoffInstitute of Plant Biochemistry, Heinrich-Heine University Düsseldorf, Düsseldorf 40225, Germany.ORCID https://orcid.org/0000-0002-3494-9420
Yi YuDepartment of Gastroenterology, Zhongnan Hospital of Wuhan University, Hubei Clinical Center and Key Laboratory of Intestinal and Colorectal Disease, School of Pharmaceutical Sciences, Wuhan University, 185 East Lake Road, Wuhan 430071, China.ORCID https://orcid.org/0000-0001-8590-0574
Julia FrunzkeInstitute of Bio-und Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich 52425, Germany.ORCID https://orcid.org/0000-0001-6209-7950

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing arms race between bacteria and phages has forced bacteria to evolve a sophisticated set of antiphage defense mechanisms that constitute the bacterial immune system. In our previous study, we highlighted the antiphage properties of aminoglycoside antibiotics, which are naturally secreted by

Indexed as

aminoglycosideaminoglycosidesinfectionsphageresistancestrains

Identifiers

PMID39205678
PMCPMC11350373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.