Evidence map›Paper›PMID 39205640›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

A novel method for determining ventilatory and gas exchange dynamics during exercise: the "chirp" waveform.

Michele Girardi, Michael A Roman, Janos Porszasz, William W Stringer, Stephen Rennard, Carrie Ferguson, Harry B Rossiter, Richard Casaburi

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michele GirardiInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0001-8102-7384
Michael A RomanDivision of Respiratory Medicine, Department of Internal Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-3954-7073
Janos PorszaszInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0002-5823-0031
William W StringerInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0003-2756-6728
Stephen RennardDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States.ORCID 0000-0001-7909-0253
Carrie FergusonInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0001-5235-1505
Harry B RossiterInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0002-7884-0726
Richard CasaburiInstitute of Respiratory Medicine and Exercise Physiology, Division of Respiratory and Critical Care Physiology and Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States.ORCID 0000-0002-8851-8589

Funding

Mechanism Underlying the Transduction of Epimutations from the Soma to the Male GermlineP50HD098593 · NICHD · UNIVERSITY OF NEVADA RENO · PI YAN, WEI · 2019 to 2024
$7.2M
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis PatientsR01DK122767 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RHEE, CONNIE MEEYOUNG · 2019 to 2023
$3.3M
Novel cardiopulmonary exercise testing variables to differentiate neuromuscular deconditioning from diseaseR01HL166850 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI Harry B Rossiter · 2023 to 2026
$3.1M
COPD Cachexia: Deciphering the Impact of Antioxidants, Iron and Mitochondrial Function Using 'Omics ApproachesR01HL153460 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCDONALD DONNELLY, MERRY-LYNN NOELLE · 2021 to 2024
$2.7M
Determinants of 5 Year Progression of Muscle Dysfunction and Inactivity in COPDGene Participants Diversity SupplementR01HL151452 · NHLBI · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI ADAMI, ALESSANDRA, ROSSITER, HARRY B · 2020 to 2023
$1.6M
Department of Defense / USAMRAA HT9425-24-1-0249HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) P50HD098593HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL151452HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL153460HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL166850HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK122767Johnny Carson FoundationNHLBI NIH HHS R01 HL151452NHLBI NIH HHS R01 HL153460NHLBI NIH HHS R01 HL166850NICHD NIH HHS P50 HD098593NIDDK NIH HHS R01 DK122767Tobacco-Related Disease Research Program (TRDRP) T31IP1666
6 · The paper itself

Abstract

Quantitating exercise ventilatory and gas exchange dynamics affords insights into physiological control processes and cardiopulmonary dysfunction. We designed a novel waveform, the chirp waveform, to efficiently extract moderate-intensity exercise response dynamics. In the chirp waveform, work rate fluctuates sinusoidally with constant amplitude as sinusoidal period decreases progressively from ∼8.5 to 1.4 min over 30 min of cycle ergometry. We hypothesized that response dynamics of pulmonary ventilation (V̇e) and gas exchange [oxygen uptake (V̇o

Indexed as

ExerciseOxygen ConsumptionPulmonary Gas ExchangePulmonary VentilationAdultAgedCarbon DioxideExercise TestFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveYoung AdultCarbon Dioxidecardiopulmonary exercise testinggas exchange kineticsmodelingsinusoidal exercisesystem identification

Identifiers

PMID39205640
PMCPMC11563590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.