Evidence map›Paper›PMID 39205638›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

Neural and muscular contributions to the age-related differences in peak power of the knee extensors in men and women.

David J Wrucke, Andrew Kuplic, Mitchell D Adam, Sandra K Hunter, Christopher W Sundberg

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Sex hormones and menopause hormone therapy predict muscle strength across the lifespan.Journal of applied physiology (Bethesda, Md. : 1985) · 2026
    Article
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  10. Effects of acidosis and inorganic phosphate on CaAmerican journal of physiology. Cell physiology · 2026
    Article
  11. Motor performance and aging in males and females.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Effects of digital physical activity interventions on muscle mechanical function in community-dwelling older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Review
  16. The relationship between voluntary and electrically evoked muscle contractile properties in young women.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025
    Article
  17. Cumulative effects of HThe Journal of physiology · 2025
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

David J WruckeExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin, United States.ORCID 0000-0003-4842-1405
Andrew KuplicExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin, United States.
Mitchell D AdamExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin, United States.
Sandra K HunterExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin, United States.ORCID 0000-0001-8013-2051
Christopher W SundbergExercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, Wisconsin, United States.ORCID 0000-0002-6709-4078

Funding

Fatigability of Limb Muscle in Older Adults: Protective Effects of ExerciseR01AG048262 · NIA · MARQUETTE UNIVERSITY · PI FITTS, ROBERT H, HUNTER, SANDRA K · 2015 to 2024
$6.1M
Motor Function in Older Adults: the Importance of Apolipoprotein-E ε4 InheritancR21AG045766 · NIA · MARQUETTE UNIVERSITY · PI HUNTER, SANDRA K · 2014 to 2015
$413k
Mechanisms of Neuromuscular Fatigue with AgingF31AG052313 · NIA · MARQUETTE UNIVERSITY · PI SUNDBERG, CHRISTOPHER · 2016 to 2017
$53k
American Heart Association (AHA) 19POST34380411HHS | NIH | National Institute on Aging (NIA) AG045766HHS | NIH | National Institute on Aging (NIA) AG048262HHS | NIH | National Institute on Aging (NIA) AG052313NIA NIH HHS F31 AG052313NIA NIH HHS R01 AG048262NIA NIH HHS R21 AG045766
6 · The paper itself

Abstract

The mechanisms for the loss in limb muscle power output in old (60-79 yr) and very old (≥80 yr) adults and whether the mechanisms differ between men and women are not well understood. We compared maximal peak power of the knee extensor muscles between young, old, and very old men and women and identified the neural and muscular factors contributing to the age-related differences in power. Thirty-one young (22.9 ± 3.0 yr, 15 women), 82 old (70.3 ± 4.9 yr, 38 women), and 16 very old adults (85.8 ± 4.2 yr, 9 women) performed maximal isokinetic contractions at 14 different velocities (30-450°/s) to identify peak power. Voluntary activation (VA) and contractile properties were assessed with transcranial magnetic stimulation to the motor cortex and electrical stimulation of the femoral nerve. The age-related loss in peak power was ∼6.5 W·yr

Indexed as

AgingKneeMuscle ContractionMuscle, SkeletalAdultAgedAged, 80 and overElectric StimulationElectromyographyFemaleFemoral NerveHumansKnee JointMaleMiddle AgedMotor Cortexagingcontractile propertiespower-velocitysex differencesvoluntary activation

Identifiers

PMID39205638
PMCPMC11486474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.