Evidence map›Paper›PMID 39205281›Full record

ArticleViruses2024

Treatment of Plantar Warts with a Nitric-Zinc Complex Solution: A Review of 72 Cases.

Sara Garcia-Oreja, Francisco Javier Alvaro-Afonso, Paula Vigara-Aranda, Guillermo Paramio-Rodriguez, Diego Leon-Herce, Jose Luis Lazaro-Martinez

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara Garcia-OrejaFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2937-7122
Francisco Javier Alvaro-AfonsoFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-4674-3822
Paula Vigara-ArandaFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.
Guillermo Paramio-RodriguezFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.
Diego Leon-HerceFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0009-0009-7973-9652
Jose Luis Lazaro-MartinezFacultad de Enfermería, Fisioterapia y Podología, University Podiatric Clinic, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6110-0265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are multiple conservative treatment options for plantar warts, but none have proven to be universally effective. Nitric acid is often used empirically by podiatrists in the treatment of plantar warts. A novel medical device or topical solution of nitric-zinc complex solution (NZCS) could potentially offer an effective and safe alternative for the targeted treatment of plantar warts.

objectiveTo observe the rate of complete healing of NZCS in a series of plantar wart cases and to establish the minimum number of product applications and time needed for healing. This will help standardize and protocolize its use.

methodsA descriptive study was conducted involving 72 patients who exhibited symptoms of plantar warts. These patients underwent chemical treatment using a nitric-zinc complex.

resultsThe cure rate with NZCS was 59.2%. The average number of NZCS applications was 5.9 ± 3.0 and the mean duration of treatment was 9.4 ± 7.1 weeks. A recurrence rate of 6.7% was observed.

conclusionsThe topical solution of the nitric-zinc complex is an effective treatment for plantar warts, which can be considered a first-line treatment option in the general population.

Indexed as

WartsZincAdministration, TopicalAdolescentAdultChildFemaleHumansMaleMiddle AgedNitric AcidTreatment OutcomeYoung AdultNitric AcidZinccutaneous wartshuman papillomavirusnitric–zinc complex solutionplantar warts

Identifiers

PMID39205281
PMCPMC11358920

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.