Evidence map›Paper›PMID 39205272›Full record

ArticleViruses2024

Re-Emergence of DENV-3 in French Guiana: Retrospective Analysis of Cases That Circulated in the French Territories of the Americas from the 2000s to the 2023-2024 Outbreak.

Alisé Lagrave, Antoine Enfissi, Sourakhata Tirera, Magalie Pierre Demar, Jean Jaonasoa, Jean-François Carod, Tsiriniaina Ramavoson, Tiphanie Succo, Luisiane Carvalho, Sophie Devos and 6 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alisé LagraveArbovirus National Reference Center, Virology Unit, Institut Pasteur de la Guyane, Cayenne 97300, French Guiana.
Antoine EnfissiArbovirus National Reference Center, Virology Unit, Institut Pasteur de la Guyane, Cayenne 97300, French Guiana.
Sourakhata TireraArbovirus National Reference Center, Virology Unit, Institut Pasteur de la Guyane, Cayenne 97300, French Guiana.ORCID 0000-0001-9311-7889
Magalie Pierre DemarLaboratoire Centre Hospitalier de Cayenne, Cayenne 97300, French Guiana.ORCID 0000-0003-3414-0821
Jean JaonasoaLaboratoire Centre Hospitalier de Cayenne, Cayenne 97300, French Guiana.
Jean-François CarodDepartment of Biology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni 97320, French Guiana.
Tsiriniaina RamavosonDepartment of Biology, West French Guiana Hospital Center, Saint-Laurent-du-Maroni 97320, French Guiana.
Tiphanie SuccoSanté Publique France, Cellule Guyane, Cayenne 97300, French Guiana.
Luisiane CarvalhoSanté Publique France, Cellule Guyane, Cayenne 97300, French Guiana.
Sophie DevosSanté Publique France, Cellule Guyane, Cayenne 97300, French Guiana.
Frédérique DorleansSanté Publique France, Cellule Antilles, French Caribbean Islands.
Lucie LeonSanté Publique France, Cellule Antilles, French Caribbean Islands.
Alain Berlioz-ArthaudLaboratoires Eurofins Guyane, French Guiana.
Didier MussoLaboratoires Eurofins Guyane, French Guiana.
Anne LavergneArbovirus National Reference Center, Virology Unit, Institut Pasteur de la Guyane, Cayenne 97300, French Guiana.
Dominique RoussetArbovirus National Reference Center, Virology Unit, Institut Pasteur de la Guyane, Cayenne 97300, French Guiana.ORCID 0000-0002-1473-3147

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

French Guiana experienced an unprecedented dengue epidemic during 2023-2024. Prior to the 2023-2024 outbreak in French Guiana, DENV-3 had not circulated in an epidemic manner since 2005. We therefore studied retrospectively the strains circulating in the French Territories of the Americas (FTA)-French Guiana, Guadeloupe, and Martinique-from the 2000s to the current epidemic. To this end, DENV-3 samples from the collection of the National Reference Center for Arboviruses in French Guiana (NRCA-FG) were selected and sequenced using next-generation sequencing (NGS) based on Oxford Nanopore Technologies, ONT. Phylogenetic analysis showed that (i) the 97 FTA sequences obtained all belonged to genotype III (GIII); (ii) between the 2000s and 2013, the regional circulation of the GIII American-I lineage was the source of the FTA cases through local extinctions and re-introductions; (iii) multiple introductions of lineages of Asian origin appear to be the source of the 2019-2021 epidemic in Martinique and the 2023-2024 epidemic in French Guiana. Genomic surveillance is a key factor in identifying circulating DENV genotypes, monitoring strain evolution, and identifying import events.

Indexed as

DengueDengue VirusDisease OutbreaksGenotypePhylogenyFrench GuianaGuadeloupeHigh-Throughput Nucleotide SequencingHumansMartiniqueRetrospective StudiesRNA, ViralRNA, ViralDENV-3DENV monitoringmolecular epidemiologyNGSre-emergence

Identifiers

PMID39205272
PMCPMC11360160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.