Evidence map›Paper›PMID 39205268›Full record

ReviewViruses2024

EBV Reactivation and Disease in Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients and Its Impact on HSCT Outcomes.

Nancy Law, Cathy Logan, Randy Taplitz

Abstract readReview
In one paragraph

Review in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nancy LawDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, La Jolla, CA 92093, USA.ORCID 0000-0002-2846-2691
Cathy LoganDivision of Infectious Diseases and Global Public Health, Department of Medicine, University of California, La Jolla, CA 92093, USA.ORCID 0000-0002-3895-952X
Randy TaplitzDivision of Infectious Diseases, Department of Medicine, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0002-0109-5991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acquisition or reactivation of Epstein-Barr virus (EBV) after allogeneic Hematopoietic Stem Cell Transplant (HSCT) can be associated with complications including the development of post-transplant lymphoproliferative disorder (PTLD), which is associated with significant morbidity and mortality. A number of risk factors for PTLD have been defined, including T-cell depletion, and approaches to monitoring EBV, especially in high-risk patients, with the use of preemptive therapy upon viral activation have been described. Newer therapies for the preemption or treatment of PTLD, such as EBV-specific cytotoxic T-cells, hold promise. Further studies to help define risks, diagnosis, and treatment of EBV-related complications are needed in this at-risk population.

Indexed as

Epstein-Barr Virus InfectionsHematopoietic Stem Cell TransplantationHerpesvirus 4, HumanLymphoproliferative DisordersTransplantation, HomologousVirus ActivationHumansRisk Factorsallogeneic transplantEBV-specific cytotoxic T-cellsEpstein–Barr viruspost-transplant lymphoproliferative disorder

Identifiers

PMID39205268
PMCPMC11359191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.