Evidence map›Paper›PMID 39205251›Full record

ArticleViruses2024

Polysubstance Use and Related Risk Behaviors among People Who Inject Drugs in Kenya Preparing for Hepatitis C Virus Treatment.

Lindsey R Riback, Mercy Nyakowa, John A Lizcano, Chenshu Zhang, Peter Cherutich, Ann E Kurth, Matthew J Akiyama

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lindsey R RibackDepartment of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.ORCID 0000-0001-8805-270X
Mercy NyakowaKenya Ministry of Health, National AIDS&STI Control Program (NASCOP), 19361 Nairobi, Kenya.
John A LizcanoYale School of Nursing, Yale University, Orange, CT 06477, USA.
Chenshu ZhangDepartment of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.
Peter CherutichKenya Ministry of Health, National AIDS&STI Control Program (NASCOP), 19361 Nairobi, Kenya.
Ann E KurthNew York Academy of Medicine, New York, NY 10029, USA.
Matthew J AkiyamaDepartment of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10461, USA.

Funding

Test and Linkage to Care (TLC_IDU) KenyaR01DA032080 · NIDA · YALE UNIVERSITY · PI CHERUTICH, PETER KIPKOECH, KURTH, ANN ELIZABETH · 2011 to 2015
$4.1M
Leveraging community health workers to improve SARS-CoV-2 testing and mitigation among criminal justice-involved individuals accessing a corrections-focused community-based organizationR01MD016744 · NIMHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Matthew Akiyama · 2021 to 2026
$3.5M
Leveraging HCV Phylogenetic Networks to Prevent HIV and Other Blood Borne Infections Among People Who Inject DrugsDP2DA053730 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI AKIYAMA, MATTHEW · 2021 to 2021
$2.5M
A Decentralized, Status neutral, Stakeholder-engaged, post-incarceration intervention for people with and at risk for HIVR61DA060627 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI AKIYAMA, MATTHEW · 2024 to 2024
$963k
Advance Care Coordination and Enhanced Linkage and Retention Among Transitional Re-Entrants LivingR00DA043011 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI AKIYAMA, MATTHEW · 2020 to 2022
$747k
National Institute on Drug Abuse, National Institutes of Health R01DA032080NIDA NIH HHS DP2 DA053730NIDA NIH HHS R00 DA043011NIDA NIH HHS R61 DA060627NIMHD NIH HHS R01 MD016744
6 · The paper itself

Abstract

Polysubstance use (PSU), injection drug use (IDU), and equipment sharing are associated with bloodborne infection (BBI) transmission risk, particularly Hepatitis C Virus (HCV), yet data on PSU in low- and middle-income countries (LMICs) is limited. We report on baseline PSU, medication-assisted treatment (MAT) engagement, and motivation to reduce IDU among 95 people who inject drugs (PWID) who accessed needle and syringe programs (NSP) in Nairobi and Coastal Kenya prior to HCV treatment. Bivariate and multivariate logistic regression were used to examine the associations between PSU and behaviors that confer HCV transmission and acquisition risks. Most participants (70.5%) reported PSU in the last 30 days, and one-third (35.8%) reported PSU exclusive to just heroin and cannabis use. Common combinations were heroin and cannabis (49.3%), and heroin, cannabis, and bugizi (flunitrazepam) (29.9%). Participants at baseline were receiving MAT (69.5%), already stopped or reduced IDU (30.5%), and were HIV-positive (40%). PSU was significantly associated with IDU (

Indexed as

Hepatitis CRisk-TakingSubstance Abuse, IntravenousAdultFemaleHepacivirusHumansKenyaMaleMiddle AgedNeedle SharingSubstance-Related DisordersYoung AdultHepatitis C Virus (HCV)injection drug use (IDU)low- and middle-income country (LMIC)people who inject drugs (PWID)polysubstance use (PSU)sub-Saharan Africa (SSA)

Identifiers

PMID39205251
PMCPMC11359571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.