Evidence map›Paper›PMID 39205248›Full record

ArticleViruses2024

The Role of Wild Boar as Host of Japanese Encephalitis Virus in the Absence of Domestic Pigs.

Fuka Kikuchi, Ai Hayashi, Karen Yamada, Yusuke Matsui, Reiko Shimbashi, Yuji Noguchi, Kazunori Tachibana, Tetsuya Mizutani, Akihiko Tokaji, Akira Yoshikawa and 5 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fuka KikuchiCenter for Infectious Diseases Epidemiology and Prevention Research, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0003-1815-7113
Ai HayashiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Karen YamadaCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Yusuke MatsuiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Reiko ShimbashiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Yuji NoguchiNagasaki Prefecture Tsushima Hospital, Nagasaki 817-0322, Japan.
Kazunori TachibanaNagasaki Prefecture Kamitsushima Hospital, Nagasaki 817-1701, Japan.
Tetsuya MizutaniCenter for Infectious Diseases Epidemiology and Prevention Research, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Akihiko TokajiDepartment of Health Policy, Kochi Public Health and Environmental Science Research Institute, Kochi 780-0850, Japan.
Akira YoshikawaDepartment of Public Health, Nagasaki Prefectural Institute for Environmental Research and Public Health, Nagasaki 856-0026, Japan.
Motoki IharaDepartment of Public Health, Nagasaki Prefectural Institute for Environmental Research and Public Health, Nagasaki 856-0026, Japan.
Kazunori OishiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.ORCID 0000-0001-5919-7520
Hajime KamiyaCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Satoru AraiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.ORCID 0000-0001-5865-0717
Motoi SuzukiCenter for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.

Funding

Japan Agency for Medical Research and Development (AMED) JP16fk0108202, JP17fk0108302, JP20fk0108066, JP22fk0108612, and JP24fk0108710
6 · The paper itself

Abstract

Pigs are the most common amplifying hosts of the Japanese encephalitis virus (JEV). In 2016, four residents on Tsushima Island who did not own pig farms were diagnosed with JE. Therefore, a serosurvey was conducted to estimate the risk and seroprevalence of JEV after the outbreak. Sera collected from 560 Tsushima Island residents between January and September 2017 were tested for neutralizing antibodies against JEV strains JaGAr01 (genotype 3) and Muar (genotype 5). Sera collected from six wild boars between June and July 2022 were tested. The seroprevalence rates of neutralizing antibodies against JaGAr01 and Muar were 38.8% and 24.6%, respectively. High anti-JEV neutralizing antibody titers of ≥320 were identified in 16 residents, including 3 younger than 6 years with prior JEV vaccination, 2 in their 40s, and 11 older than 70. However, no anti-JEV-specific IgM was detected. Residents who engaged in outdoor activities had higher anti-JEV antibody titers. Sera from wild boars were negative for JEV RNA, but four of six samples contained neutralizing antibodies against JEV. Therefore, JEV transmission continues on Tsushima Island, even in the absence of pig farms, and wild boars might serve as the amplifying hosts.

Indexed as

Antibodies, NeutralizingAntibodies, ViralEncephalitis, JapaneseEncephalitis Virus, JapaneseSus scrofaSwine DiseasesAnimalsFemaleGenotypeHumansJapanMaleSeroepidemiologic StudiesSwineAntibodies, NeutralizingAntibodies, ViralboarsJapanese encephalitisoutbreakseroprevalenceserosurvey

Identifiers

PMID39205248
PMCPMC11360753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.