Evidence map›Paper›PMID 39204425›Full record

ArticlePharmaceutics2024

Poly(2-Deoxy-2-Methacrylamido-D-Glucose)-Based Complex Conjugates of Colistin, Deferoxamine and Vitamin B12: Synthesis and Biological Evaluation.

Mariia Stepanova, Mariia Levit, Tatiana Egorova, Yulia Nashchekina, Tatiana Sall, Elena Demyanova, Ivan Guryanov, Evgenia Korzhikova-Vlakh

Abstract read
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In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariia StepanovaInstitute of Macromolecular Compounds of Russian Academy of Sciences, 199004 St. Petersburg, Russia.ORCID 0000-0002-8385-4321
Mariia LevitInstitute of Macromolecular Compounds of Russian Academy of Sciences, 199004 St. Petersburg, Russia.ORCID 0000-0002-2136-1329
Tatiana EgorovaInstitute of Highly Pure Biopreparations, 197110 St. Petersburg, Russia.
Yulia NashchekinaInstitute of Cytology of Russian Academy of Sciences, 194064 St. Petersburg, Russia.
Tatiana SallInstitute of Experimental Medicine, 197022 St. Petersburg, Russia.ORCID 0000-0002-5890-5641
Elena DemyanovaInstitute of Highly Pure Biopreparations, 197110 St. Petersburg, Russia.
Ivan GuryanovInstitute of Chemistry, St. Petersburg State University, 198504 St. Petersburg, Russia.ORCID 0000-0001-6897-3528
Evgenia Korzhikova-VlakhInstitute of Macromolecular Compounds of Russian Academy of Sciences, 199004 St. Petersburg, Russia.ORCID 0000-0002-2530-7709

Funding

Russian Science Foundation 19-73-20157
6 · The paper itself

Abstract

Growing resistance to traditional antibiotics poses a global threat to public health. In this regard, modification of known antibiotics, but with limited applications due to side effects, is one of the extremely promising approaches at present. In this study, we proposed the synthesis of novel complex polymeric conjugates of the peptide antibiotic colistin (CT). A biocompatible and water-soluble synthetic glycopolymer, namely, poly(2-deoxy-2-methacrylamido-

Indexed as

antimicrobial activitycolistincomplex conjugatescovalent conjugatesdeferoxaminein vitro permeability assaypolymyxinssiderophoresynthetic glycopolymervitamin B12

Identifiers

PMID39204425
PMCPMC11359296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.