Evidence map›Paper›PMID 39204343›Full record

ArticlePharmaceutics2024

Enhanced Antibacterial Efficacy of Bioceramic Implants Functionalized with Ciprofloxacin: An In Silico and In Vitro Study.

Renata-Maria Văruț, Luciana Teodora Rotaru, Diana Cimpoesu, Mihaela Corlade, Cristina Elena Singer, Alin Iulian Silviu Popescu, Cristina Popescu, Iliescu Iulian-Nicolae, Adriana Mocanu, Mihaela Popescu and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Renata-Maria VăruțResearch Methodology Department, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Luciana Teodora RotaruEmergency Medicine and First Aid Department, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-3135-5456
Diana CimpoesuEmergency St. Spiridon Hospital, Faculty of Medicine, University of Medicine and Pharmacy Gr. T. Popa, 700115 Iasi, Romania.ORCID 0000-0003-0609-3773
Mihaela CorladeEmergency St. Spiridon Hospital, Faculty of Medicine, University of Medicine and Pharmacy Gr. T. Popa, 700115 Iasi, Romania.
Cristina Elena SingerDepartment of Mother and Baby, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Alin Iulian Silviu PopescuDepartment of Internal Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Cristina PopescuDepartment of Anatomy, University of Medicine and Pharmacy, Discipline of Anatomy, 200349 Craiova, Romania.ORCID 0009-0001-6745-9823
Iliescu Iulian-NicolaeDepartment of Mother and Baby, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0009-0004-4406-7087
Adriana MocanuPharmacist at the Military Emergency Clinical Hospital, 200749 Craiova, Romania.
Mihaela PopescuDepartment of Endocrinology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mihai Alexandru ButoiEmergency Medicine and First Aid Department, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Oana Elena NicolaescuDepartment of Pharmaceutical Technique, University of Medicine and Pharmacy, Discipline of Anatomy, 200349 Craiova, Romania.ORCID 0000-0003-1815-780X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explores the antibacterial efficacy and cytotoxicity of ciprofloxacin-functionalized bioceramic implants. We synthesized hydroxyapatite-ciprofloxacin (HACPX

Indexed as

antibioticsbone infectionsmolecular docking

Identifiers

PMID39204343
PMCPMC11358898

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.