ReviewPathogens (Basel, Switzerland)2024
Invasive Candida Infections in Neonatal Intensive Care Units: Risk Factors and New Insights in Prevention.
Review in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Guideline for the diagnosis and treatment of common neonatal diseases in primary healthcare institutions: neonatal infectious pneumonia (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatricsGuideline
- Neonatal candidemia over seven years: Epidemiological trends, risk factors, and outcome associations with Paed-EQUAL Candida score adherence.European journal of pediatrics · 2026Article
- Neonatal Candidemia: Clinical Characteristics and Predictors of 28-Day Mortality.Journal of fungi (Basel, Switzerland) · 2026Article
- Candidemia Epidemiology and Antifungal Resistance in Critically-ill Patients During and After COVID-19 Pandemic: Comparison Between Two Hospitals in Greece and Türkiye.Mycopathologia · 2026Article
- Neonatal Candida infections in Brazil: study on virulence and antifungal susceptibility with predominance of non-albicans Candida.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Observational
- Overview of Risk Factors and Diagnosis of Invasive Candidiasis.Journal of fungi (Basel, Switzerland) · 2026Review
- Burden, clinical characteristics, and determinants of neonatal sepsis in a tertiary hospital in North-Central Nigeria: a retrospective study.BMC pediatrics · 2026Article
- Antifungal susceptibility, FKS1 gene expression, and virulence determinants of Candida albicans in pediatric and neonatal candidiasis.BMC infectious diseases · 2026Article
- Neonatal Candidemia in Latin America: Trends, Resistance, and Prevention Strategies (2008-2025).Journal of fungi (Basel, Switzerland) · 2026Review
- Assessment of skin yeast colonization and its predisposing factors among neonates admitted to the neonatal intensive care unit.BMC infectious diseases · 2026Article
- The Gut as a Source of Infection for Fungal Pathogens: Increased Fecal Candida albicans Precedes Onset of Candida Late-Onset Sepsis in Very Preterm Infants.The Journal of infectious diseases · 2026Article
- Irrational and Inappropriate Use of Antifungals in the NICU: A Narrative Review.Antibiotics (Basel, Switzerland) · 2026Review
- Hemodynamic profile of neonatal fungal sepsis with insights into the disease spectrum: a retrospective study.Frontiers in pediatrics · 2026Article
- Neonatal and pediatric sepsis: Microbiological insights, diagnostic innovations, and antimicrobial challenges.World journal of clinical pediatrics · 2025Review
- The accuracy of the Candida ScoreAnnals of medicine · 2025Article
- Emerging Treatments in Neonatal Fungal Infections: Progress and Prospects.Paediatric drugs · 2025Review
- Characterization and virulence of yeasts associated with neonatal thrush.BMC microbiology · 2025Article
- Clinical features, risk factors, and outcomes of neonatal invasive candidiasis: a 20-case study series from a tertiary neonatal critical care unit in Oman.Italian journal of pediatrics · 2025Article
- A 10-Year Study of Neonatal Sepsis from Tuen Mun Hospital, Hong Kong.Pathogens (Basel, Switzerland) · 2025Article
- A cell wall-targeting urease-derived peptide as a potential antifungal agent againstCurrent research in microbial sciences · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Invasive Candida infections represent a significant cause of morbidity and mortality in neonatal intensive care units (NICUs), with a particular impact on preterm and low-birth-weight neonates. In addition to prematurity, several predisposing factors for Candida colonization and dissemination during NICU hospitalization have been identified, including prolonged exposure to broad-spectrum antibiotics, central venous catheters, parenteral nutrition, corticosteroids, H2 antagonist administration, and poor adherence to infection control measures. According to the literature, the implementation of antifungal prophylaxis, mainly fluconazole, in high-risk populations has proven to be an effective strategy in reducing the incidence of fungal infections. This review aims to provide an overview of risk factors for invasive Candida infections and current perspectives regarding antifungal prophylaxis use. Recognizing and reducing people's exposure to these modifiable risk factors, in conjunction with the administration of antifungal prophylaxis, has been demonstrated to be an effective method for preventing invasive candidiasis in susceptible neonatal populations.
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