Evidence map›Paper›PMID 39204225›Full record

ArticlePathogens (Basel, Switzerland)2024

Carriage Rate of Enterobacterales Resistant to Extended-Spectrum Cephalosporins in the Tunisian Population.

Ahlem Mahjoub Khachroub, Meriem Souguir, Pierre Châtre, Nour Elhouda Bouhlel, Nadia Jaidane, Antoine Drapeau, Marah El Kantaoui, Sana Azaiez, Jean-Yves Madec, Wejdene Mansour and 1 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahlem Mahjoub KhachroubLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Meriem SouguirLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Pierre ChâtreUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.ORCID 0000-0003-4294-2824
Nour Elhouda BouhlelLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Nadia JaidaneLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Antoine DrapeauUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Marah El KantaouiLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Sana AzaiezLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Jean-Yves MadecUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.
Wejdene MansourLaboratoire de Recherche Biophysique Métabolique et Pharmacologie Appliquée, LR12ES02, Faculté de Médecine Ibn Al Jazzar Sousse, Université de Sousse, Sousse 4002, Tunisia.
Marisa HaenniUnité Antibiorésistance et Virulence Bactériennes, ANSES-Université de Lyon, 69007 Lyon, France.ORCID 0000-0003-1333-5603

Funding

ANSES no number - internal funding
6 · The paper itself

Abstract

Enterobacterales resistant to extended-spectrum cephalosporins (ESC) are a marker of the antimicrobial resistance (AMR) burden. They are infecting humans, but the intestinal microbiota can also be transiently colonized without developing symptoms. Healthy carriage can promote silent dissemination of resistant bacteria, and data on this colonization are often lacking. Between 2021 and 2023, a sampling of healthy Tunisian people was carried out. Fecal samples (n = 256) were plated on selective agar, and all collected isolates were characterized by phenotypic (antibiograms) and genomic (whole-genome sequencing) methods. A total of 26 (26/256, 10.2%) isolates were collected, including 24

Indexed as

Anti-Bacterial AgentsCephalosporinsEscherichia coliKlebsiella pneumoniaeMicrobial Sensitivity TestsAdultbeta-LactamasesCarrier StateEnterobacteriaceaeEnterobacteriaceae InfectionsFecesFemaleHumansMaleMiddle AgedTunisiaAnti-Bacterial Agentsbeta-LactamasesCephalosporinsESBLF-:A-:B53plasmidST349Tunisia

Identifiers

PMID39204225
PMCPMC11356955

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.