Evidence map›Paper›PMID 39203981›Full record

ReviewVaccines2024

Global Seroprevalence of Tick-Borne Encephalitis Antibodies in Humans, 1956-2022: A Literature Review and Meta-Analysis.

Patrick H Kelly, Pingping Zhang, Gerhard Dobler, Kate Halsby, Frederick J Angulo, Andreas Pilz, Harish Madhava, Jennifer C Moïsi

Abstract readReview
In one paragraph

Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patrick H KellyVaccines and Antivirals Medical Affairs, Pfizer US Commercial Division, New York, NY 10001-2192, USA.ORCID 0000-0002-5155-6741
Pingping ZhangMedical Affairs Evidence Generation Statistics, Pfizer Global Product Development Group, Collegeville, PA 19426-3982, USA.ORCID 0009-0003-5716-820X
Gerhard DoblerBundeswehr Institute for Microbiology, National TBEV Consultant Laboratory, 80937 Munchen, Germany.ORCID 0000-0001-7461-293X
Kate HalsbyVaccines and Antivirals Medical Affairs, Pfizer Biopharma Group, Tadworth KT20 7NS, UK.
Frederick J AnguloVaccines and Antivirals Medical Affairs, Pfizer US Commercial Division, New York, NY 10001-2192, USA.ORCID 0000-0002-3120-7704
Andreas PilzVaccines and Antivirals Medical Affairs, Pfizer Biopharma Group, 1210 Vienna, Austria.ORCID 0000-0002-6394-3845
Harish MadhavaVaccines and Antivirals Medical Affairs, Pfizer Biopharma Group, Tadworth KT20 7NS, UK.
Jennifer C MoïsiVaccines and Antivirals Medical Affairs, Pfizer Biopharma Group, 75014 Paris, France.

Funding

Pfizer (internal funding)
6 · The paper itself

Abstract

Despite the availability of tick-borne encephalitis (TBE) vaccines, the incidence of TBE is increasing. To understand the historical patterns of infection, we conducted a global meta-analysis of studies before December 2023 reporting human antibody prevalence against TBEV (TBE virus) among general or high-risk population groups stratified by country, collection year, serological method, and vaccination status. Pooled data were compared within groups over time by random-effects modeling. In total, 2403 articles were retrieved; 130 articles published since 1959 were included. Data were extracted from 96 general populations (117,620 participants) and 71 high-risk populations (53,986 participants) across 33 countries. Germany had the most population groups (21), and Poland had the most participants (44,688). Seven serological methods were used; conventional IgG/IgM ELISAs were the most common (44%). Four studies (1.7%) used NS1-ELISA serology. Between 1956-1991 and 1992-2022, anti-TBEV seroprevalence remained at ~2.75% across all population groups from "high-risk" areas (

Indexed as

FlaviviridaeflavivirusIxodesOrthoflavivirusseroprevalenceTBEticktick-borne encephalitis

Identifiers

PMID39203981
PMCPMC11360530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.