Evidence map›Paper›PMID 39203968›Full record

ArticleVaccines2024

A Serological Survey of Measles and Rubella Antibodies among Different Age Groups in Eastern China.

Rui Yan, Hanqing He, Xuan Deng, Yang Zhou, Xuewen Tang, Yao Zhu, Hui Liang, Yaping Chen, Mengya Yang, Yuxia Du and 4 more

Abstract read
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rui YanDepartment of Emergency Medicine, Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou 310000, China.ORCID 0000-0001-7254-0725
Hanqing HeZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Xuan DengZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.ORCID 0000-0002-7299-6527
Yang ZhouZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Xuewen TangZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Yao ZhuZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Hui LiangZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Yaping ChenZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Mengya YangZhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310057, China.
Yuxia DuDepartment of Emergency Medicine, Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou 310000, China.
Can ChenDepartment of Emergency Medicine, Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou 310000, China.
Jiaxin ChenDepartment of Emergency Medicine, Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou 310000, China.
Shigui YangDepartment of Emergency Medicine, Department of Epidemiology and Biostatistics, School of Public Health, Zhejiang University School of Medicine, Second Affiliated Hospital, Hangzhou 310000, China.
Ridphe Group

Funding

he Mega-Project of National Science and Technology for the 13th Five-Year Plan of China 2018ZX10715-014-002the National Natural Science Foundation of China 81672005the National Natural Science Foundation of China 82173577the National Natural Science Foundation of China U23A20496the Zhejiang Provincial Medical and Health Science and Technology Project 2022KY721
6 · The paper itself

Abstract

backgroundMeasles and rubella are vaccine-preventable diseases targeted for elimination in most World Health Organization regions, and China is considered to have momentum towards measles elimination. Therefore, this study aimed to assess the population immunity levels against measles and rubella in Zhejiang Province in China in order to provide valuable insights for informing future public health measures and contributing to the ongoing global campaign against these diseases. MATERIALS AND

methodsA cross-sectional serological survey was conducted in 2022. A total of 2740 blood samples were collected from healthy individuals spanning the age range of 0-59 years, representing diverse demographic strata across 11 prefectures in Zhejiang Province in China. The sera were tested for measles and rubella IgG antibodies to determine positivity rates and geometric mean concentrations (GMCs).

resultsThe overall positivity rate for the measles IgG antibody was 85.3%, with a GMC of 588.30 mIU/mL. The positivity rate for the rubella IgG antibody was 70.9%, and the GMC was 35.30 IU/mL. Measles IgG antibody positivity rates across the 0-11 months, 12-23 months, 24-35 months, 3-5 years, 6-9 years, 10-14 years, 15-19 years, 20-29 years, and 30-59 years age groups were 63.1%, 92.5%, 97.0%, 94.0%, 85.8%, 77.3%, 86.9%, 84.9%, and 88.7%, respectively (trend

conclusionsThe seroprevalence of measles and rubella was lower than that required for herd immunity. Periodic vaccination campaigns should be launched to increase immunity.

Indexed as

antibody levelherd immunitymeasles virusrubella virus

Identifiers

PMID39203968
PMCPMC11359031

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.