Evidence map›Paper›PMID 39203915›Full record

Trial reportNutrients2024

Effect of Fermented Soybean (FSB) Supplementation on Gastroesophageal Reflux Disease (GERD).

Eugenie Sin Sing Tan, Rahela Zaman, Muhammad Akbar Memon, Chung Keat Tan

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06524271 (Effect of Fermented Soybean), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06524271 nacompletednot on this map

Effect of Fermented Soybean (FSB) Supplementation on Gas-troesophageal Reflux Disease (GERD)

TypeinterventionalSponsorNATTOME SDN BHDRan2023 to 2024Enrolled110ConditionsGastro Esophageal RefluxArmsFermented Soybean, Supplement without fermented soybean
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eugenie Sin Sing TanFaculty of Medicine and Health Science, UCSI University, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-5711-4808
Rahela ZamanFaculty of Medicine and Health Science, UCSI University, Kuala Lumpur 56000, Malaysia.
Muhammad Akbar MemonFaculty of Medicine and Allied Medical Sciences, Isra University, New Hala-Mirpur Khas Rd Link, Hyderabad 71000, Pakistan.
Chung Keat TanFaculty of Medicine and Health Science, UCSI University, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-3956-2217

Funding

Ministry of Higher Education FRGS/1/2022/SKK06/UCSI/02/2
6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) is a prevalent chronic condition affecting the well-being of both adults and children in general medical practice. Research on the effects of fermented soybean (SB) supplementation in managing GERD is relatively new, with limited studies available. The existing research often lacks sufficient dosing regimens and study durations to differentiate between transient placebo effects and sustained benefits. In this study, the beneficial effects of FSB supplementation were investigated in 110 voluntary participants (NCT06524271). The participants were required to take 1 g of FSB supplement once daily for 12 weeks. GERD symptoms were evaluated using the Reflux Disease Questionnaire (RDQ), while inflammatory markers, including interleukin-4 (IL-4), interleukin-6 (IL-6), and interleukin-8 (IL-8), were measured to assess inflammation. The Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire was used to evaluate participants' quality of life. The results indicated that FSB supplementation significantly (

Indexed as

Dietary SupplementsGastroesophageal RefluxGlycine maxQuality of LifeAdultFemaleFermentationFermented FoodsHumansMaleMiddle AgedSurveys and QuestionnairesYoung Adultfermented soybean (FSB)gastroesophageal reflux disease (GERD)inflammatory markersQuality of Life in Reflux and Dyspepsia (QOLRAD)reflux disease questionnaire (RDQ)

Identifiers

PMID39203915
PMCPMC11356962

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.