Evidence map›Paper›PMID 39203582›Full record

ArticleMicroorganisms2024

Diagnostic Accuracy of Rotational Thromboelastometry for Low-Virulence Periprosthetic Joint Infections: A Pilot Study.

Andreas G Tsantes, Aglaia Domouchtsidou, Konstantina A Tsante, Petros Ioannou, Alexandra Mpakosi, Eleni Petrou, Stavros Goumenos, Ioannis G Trikoupis, Anastasios G Roustemis, Sotirios P Fortis and 5 more

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Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Andreas G TsantesLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0002-3695-0759
Aglaia DomouchtsidouMicrobiology Department, "Saint Savvas" Oncology Hospital, 11522 Athens, Greece.ORCID 0000-0003-0141-4718
Konstantina A TsanteLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Petros IoannouDepartment of Internal Medicine & Infectious Diseases, University General Hospital of Heraklion, 71110 Heraklion, Greece.ORCID 0000-0003-1082-5674
Alexandra MpakosiDepartment of Microbiology, General Hospital of Nikaia "Agios Panteleimon", 18454 Piraeus, Greece.ORCID 0000-0002-9833-8477
Eleni PetrouLaboratory of Haematology and Blood Bank Unit, "Attiko" Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.
Stavros GoumenosFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Ioannis G TrikoupisFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 15771 Athens, Greece.ORCID 0000-0003-4759-4814
Anastasios G RoustemisFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Sotirios P FortisLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, Section of Medical Laboratories, School of Health & Caring Sciences, University of West Attica (UniWA), 12244 Athens, Greece.
Christos KoutserimpasOrthopaedics Surgery and Sports Medicine Department, FIFA Medical Centre of Excellence, Croix-Rousse Hospital, Lyon University Hospital, 69004 Lyon, France.ORCID 0000-0002-1398-9626
Panayiotis J PapagelopoulosFirst Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 15771 Athens, Greece.
George SamonisMetropolitan Hospital, Neon Faliron, 18547 Athens, Greece.
Stefanos BonovasDepartment of Biomedical Sciences, Humanitas University, 20072 Milan, Italy.ORCID 0000-0001-6102-6579
Dimitrios V PapadopoulosSecond Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriprosthetic joint infections (PJIs) are associated with altered coagulation dynamics; therefore, coagulation laboratory studies could be valuable for diagnosing PJI. This study aimed to evaluate the diagnostic role of Rotational Thromboelastometry (ROTEM) in detecting PJIs caused by low-virulence pathogens.

methodsA retrospective study was conducted, enrolling 78 patients who underwent exchange arthroplasty due to PJI due to high-virulence pathogens (Group A,

resultsSeveral ROTEM parameters differed in patients with PJIs caused by low-virulence pathogens, indicating a link between these infections and hypercoagulability. The development of low-virulence PJIs was associated with a higher maximum clot firmness (MCF) (Odds Ratio, 1.12; 95% Confidence Interval, 1.04-1.21;

conclusionsOur findings suggest that ROTEM analysis is a promising method for detecting the altered hemostatic dynamics associated with PJI caused by low-virulence pathogens.

Indexed as

coagulationdiagnosislow-virulence pathogensperiprosthetic joint infectionsrotational thromboelastometry

Identifiers

PMID39203582
PMCPMC11357059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.