Evidence map›Paper›PMID 39203576›Full record

ReviewMicroorganisms2024

Gut Microbes Associated with Neurodegenerative Disorders: A Comprehensive Review of the Literature.

Christos Koutsokostas, Ermis Merkouris, Apostolos Goulas, Konstantina Aidinopoulou, Niki Sini, Theofanis Dimaras, Dimitrios Tsiptsios, Christoph Mueller, Maria Nystazaki, Konstantinos Tsamakis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  13. Opposite regulatory effects ofFrontiers in neurology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christos KoutsokostasNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.
Ermis MerkourisNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.ORCID 0009-0000-6664-4405
Apostolos GoulasNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.ORCID 0009-0007-0901-8919
Konstantina AidinopoulouNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.
Niki SiniNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.
Theofanis DimarasNeurology Department, Democritus University of Thrace, 68100 Alexandroupoli, Greece.
Dimitrios Tsiptsios3rd Neurology Department, Aristotle University, 54124 Thessaloniki, Greece.ORCID 0000-0002-1601-8788
Christoph MuellerInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London SE5 8AB, UK.ORCID 0000-0001-9816-1686
Maria Nystazaki2nd Department of Psychiatry, University General Hospital 'Attikon', 12462 Athens, Greece.ORCID 0000-0002-1357-2230
Konstantinos TsamakisInstitute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London SE5 8AB, UK.ORCID 0000-0002-0063-8413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence shows that neurodegenerative and neuropsychiatric disorders are influenced by alterations in the gut microbiome. Various diseases have been linked to microbiome dysbiosis, yet there are inconclusive data regarding which microorganisms are associated with each disorder. The aim of our study is to systematically review the recent literature of the past decade to clarify whether the gut microbiome contributes to the understanding of pathogenesis and progression of neurodegenerative disorders. Most included studies showed a strong correlation between the relative abundance of certain microorganisms, mainly species of the phyla

Indexed as

alterationsAlzheimer’s diseasedysbiosisgut–brain axisgut microbiomeneurodegenerativeneuropsychiatricParkinson’s disease

Identifiers

PMID39203576
PMCPMC11357424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.