Evidence map›Paper›PMID 39203533›Full record

ArticleMicroorganisms2024

Tetsuya Chiba, Yorito Hattori, Daisuke Motooka, Tomotaka Tanaka, Masafumi Ihara

Abstract readCase Reports
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tetsuya ChibaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.ORCID 0000-0003-1939-6327
Yorito HattoriDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.ORCID 0000-0002-1495-4433
Daisuke MotookaDepartment of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 565-0871, Japan.
Tomotaka TanakaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.ORCID 0000-0002-6023-236X
Masafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center, Suita, Osaka 564-8565, Japan.ORCID 0000-0002-7102-4048

Funding

Nature Holdings N/A
6 · The paper itself

Abstract

When treating anaerobic brain abscesses, healthcare professionals often face the difficulty of identifying the causal pathogens, necessitating empiric therapies with uncertain efficacy. We present the case of a 57-year-old woman who was admitted to our hospital with a fever and headache. Brain magnetic resonance imaging revealed a hemorrhagic lesion with wall enhancement at the left hemisphere on contrast-enhanced T1-weighted imaging. Cerebrospinal fluid examination showed pleocytosis (23 cells/μL), an elevated protein level (125 mg/dL), and decreased glucose level (51 mg/dL; blood glucose was 128 mg/dL). Intracerebral hemorrhage accompanied by a brain abscess was clinically suspected. The patient received empirical treatment with intravenous meropenem and vancomycin for 2 weeks. However, conventional bacterial culture tests failed to identify the pathogen. We then performed shotgun sequencing and ribosomal multilocus sequence typing, which identified

Indexed as

brain abscessParaclostridium tenuewhole-metagenome sequencing

Identifiers

PMID39203533
PMCPMC11356858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.